Huo Yan, Schoenbauer Robert, Richter Sergio, Rolf Sascha, Sommer Philipp, Arya Arash, Rastan Ardawan, Doll Nicolas, Mohr Friedrich-Wilhelm, Hindricks Gerhard, Piorkowski Christopher, Gaspar Thomas
Department of Electrophysiology, Dresden University-Heart Center, Dresden, Germany.
J Cardiovasc Electrophysiol. 2014 Jul;25(7):725-38. doi: 10.1111/jce.12406. Epub 2014 Apr 2.
Intraoperative atrial fibrillation (AF) ablation during cardiac surgery is a well-established treatment. However, tachycardia mechanisms, ablation strategies, and long-term follow-up of atrial arrhythmias (AA) following intraoperative AF ablation (AFA) have not been previously studied in a large cohort of patients.
Eighty-two patients (48 male, median age of 65 years) with symptomatic recurrence of AA following intraoperative AFA underwent radiofrequency catheter ablation.
Regular atrial tachycardias (AT) were mapped using 3-dimensional (3D) color-coded entrainment/activation mapping and eliminated by linear ablation. Pulmonary vein (PV)-isolation (PVI) was achieved in patients with left atrium-PV (LAPV) conduction after AT elimination.
In 85 (83%) out of a total of 103 regular ATs, the entire reentrant circuits were localized perimitrally (n = 27), around PVs (left PV [LPV] or right PV [RPV]; n = 9), around left atrial appendage (LAA; n = 1), on left-sided atrial septum (n = 8), on atrioventricular nodal area (n = 1), on the posterior wall of LA (n = 1), along roof-septum-inferoposterior wall (n = 8), at coronary sinus ostium (n = 2), upper loop in RA (n = 1), and as cavotricuspid isthmus-dependent reentrant ATs (n = 27). Sixty-five (79%) patients received PVI. Noninducibility of any AT was reached at the end of all procedures. During a median follow-up time of 18 months, 69 patients (87%) were free of AA.
Reentrant AT appears in the majority of patients with recurrence of AA following intraoperative AFA. Detailed 3D color-coded entrainment mapping was successfully obtained in the majority of patients suffering from reentrant AT after intraoperative AFA, facilitated the accurate identification of the entire reentrant circuit and selection of optimal ablation lines.
心脏手术期间的术中房颤消融是一种成熟的治疗方法。然而,此前尚未在大量患者队列中研究术中房颤消融(AFA)后房性心律失常(AA)的心动过速机制、消融策略及长期随访情况。
82例(48例男性,中位年龄65岁)术中AFA后出现症状性AA复发的患者接受了射频导管消融。
使用三维(3D)彩色编码拖带/激动标测对规则房性心动过速(AT)进行标测,并通过线性消融消除。在消除AT后,对存在左心房-肺静脉(LAPV)传导的患者进行肺静脉(PV)隔离(PVI)。
在总共103次规则AT中,85次(83%)的整个折返环位于心包周围(n = 27)、肺静脉周围(左肺静脉[LPV]或右肺静脉[RPV];n = 9)、左心耳周围(LAA;n = 1)、左侧房间隔(n = 8)、房室结区域(n = 1)、左心房后壁(n = 1)、沿房顶-房间隔-下后壁(n = 8)、冠状窦口(n = 2)、右心房上环(n = 1)以及作为三尖瓣峡部依赖性折返性AT(n = 27)。65例(79%)患者接受了PVI。所有手术结束时均达到任何AT均不能诱发的状态。在中位随访时间18个月期间,69例(87%)患者未出现AA。
术中AFA后AA复发的大多数患者出现折返性AT。在大多数术中AFA后发生折返性AT的患者中成功获得了详细的3D彩色编码拖带标测,有助于准确识别整个折返环并选择最佳消融线。