Stephens R, Fan Eddy
Crit Care. 2014 Feb 20;18(1):112. doi: 10.1186/cc13736.
Refractory cardiac shock in the cardiac surgical intensive care unit confers significant morbidity and mortality. Extracorporeal membrane oxygenation (ECMO) has become a common intervention for refractory cardiogenic shock when other therapies have failed. However, it is difficult to predict who will benefit from this costly, resource-intensive, but potentially life-saving technology. Here, we discuss the utility of a novel biomarker, serum butylcholinesterase, in determining survival in patients supported with ECMO following cardiac surgery.
心脏外科重症监护病房中的难治性心源性休克会导致显著的发病率和死亡率。当其他治疗方法失败时,体外膜肺氧合(ECMO)已成为治疗难治性心源性休克的常用干预措施。然而,很难预测谁将从这种昂贵、资源密集但可能挽救生命的技术中获益。在此,我们讨论一种新型生物标志物——血清丁酰胆碱酯酶在确定心脏手术后接受ECMO支持的患者生存情况方面的效用。