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巴西南里奥格兰德州圣玛丽亚市的多发性硬化症患病率。

The prevalence of multiple sclerosis in Santa Maria, Rio Grande do Sul, Brazil.

作者信息

Finkelsztejn Alessandro, Lopes Juarez Silva, Noal Janaína, Finkelsztejn Juliana M

机构信息

Ambulatório de Esclerose Múltipla, Hospital das Clínicas de Porto Alegre, Neurologist, coordinator of the Ambulatório de Esclerose Múltipla at the Hospital de Clinicas de Porto Alegre.

Multiple Sclerosis Treatment Center, Santa MariaRS, Brazil, Neurologist, coordinator of the Multiple Sclerosis Treatment Center - Santa Maria-RS, Brazil;

出版信息

Arq Neuropsiquiatr. 2014 Feb;72(2):104-6. doi: 10.1590/0004-282X20130216.

Abstract

Multiple sclerosis (MS) is one of the leading causes of neurologic deficits in young adults and can lead to physical, intellectual and emotional problems. Approved treatments are expensive and are among the 10 highest budgets of the Brazilian Health Ministry. Given the diverse prevalence of MS among Brazilian regions, it is important to determine prevalence rates across the country. Seven studies have assessed MS in Brazil and reported rates ranging from 15 cases to 18 cases per 100,000 inhabitants. It has been hypothesized that this rate is even higher in southern Brazil, which has a high proportion of European heritage (mostly German and Italian) immigrants. Here, we report that the prevalence of MS in the city of Santa Maria, Rio Grande do Sul, Brazil, is 27.2 cases/100,000 inhabitants.

摘要

多发性硬化症(MS)是导致年轻成年人神经功能缺损的主要原因之一,可引发身体、智力和情感方面的问题。获批的治疗费用高昂,位列巴西卫生部十大最高预算项目之中。鉴于MS在巴西各地区的患病率存在差异,确定全国的患病率很重要。已有七项研究对巴西的MS情况进行了评估,报告的患病率为每10万居民中有15至18例。据推测,在巴西南部,欧洲裔(主要是德国和意大利)移民比例较高,MS患病率甚至更高。在此,我们报告巴西南里奥格兰德州圣玛丽亚市的MS患病率为每10万居民中有27.2例。

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