University of Melbourne, Florey Neuroscience and Mental Health Institute, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria 3010, Australia.
Cell Stem Cell. 2014 Mar 6;14(3):273-4. doi: 10.1016/j.stem.2014.02.009.
Two recent papers in Nature describe a remarkable new technique for reprogramming somatic cells back to the embryonic state. Obokata et al. (2014a, 2014b) show that applying stressful stimuli can convert mature cells into progenitors capable of generating all three embryonic germ layer lineages, as well as placental tissue.
两篇发表在《自然》杂志上的最新论文描述了一种将体细胞重编程回胚胎状态的非凡新技术。Obokata 等人(2014a,2014b)表明,施加应激刺激可以将成熟细胞转化为能够产生所有三种胚胎生殖层谱系以及胎盘组织的祖细胞。