Chemical Engineering Department, Sardar Vallabhbhai National Institute of Technology, Ichchhanath, Surat, Gujarat, 395007, India.
Rev Environ Contam Toxicol. 2014;230:83-110. doi: 10.1007/978-3-319-04411-8_4.
Nanotechnology offers unique attributes to various industrial and consumer sectors, and has become a topic of high interest to scientific communities across the world. Our society has greatly benefitted from nanotechnology already, in that many products with novel properties and wide applicability have been developed and commercialized. However, the increased production and use of nanomaterials have raised concerns about the environmental fate and toxicological implications of nanoparticles and nanomaterials. Research has revealed that various nanomaterials may be hazardous to living organisms. Among biota, plants are widely exposed to released nanomaterials and are sensitive to their effects. The accumulation of nannmaterials in the environment is a potential threat, not only because of potential damage to plants hut also because nanoparticles may enter the food chain. Although the literature that addresses the safety of nanoproducts is growing, little is known about the mechanisms by which these materials produce toxicity on natural species, including humans. In this paper, we have reviewed the literature relevant to what phytotoxic impact fabricated nanoparticles (e.g., carbon nanotubes, metallic and metal oxide nanoparticles, and certain other nanomaterials) have on plants. Nanoparticles produce several effects on plant physiology and morphology. Nanoparticles are known to affect root structure, seed germination, and cellular metabolism. Nanoparticles inhibit growth, induce oxidative stress, morphogenetic abnormalities and produce clastogenic disturbances in several plant species. The size, shape and surface coating of NPs play an important role in determining their level of toxicity. Of course, the dose, route of administration, type of dispersion media, and environmental exposure also contribute to how toxic nanoparticles are to plants. Currently, nanotoxicity studies are only in their initial phases of development and more research will be required to identify the actual threat nanoproducts pose to the plant system. To date, data show that there is a large variation in the phytotoxicity caused by different NPs. Moreover, the studies conducted thus far have mostly relied on microscopy to detect effects. Studies that incorporate measures and analyses undertaken with more modern tools are needed. Among new data that are most urgently needed on NPs is how fabricated NPs behave once released into the environment, and how exposure to them may affect plant resistance, metabolic pathways, and plant genetic responses. In this review, we have attempted to collect, present and summarize recent findings from the literature on nanoparticle toxicity in plants. To strengthen the analysis, we propose a scheme for accessing NP toxicity. We also recommend how the potential challenges presented by increased production and release of NPs should be addressed. It is our belief and recommendation that every nanomaterial-based product be subjected to appropriate toxicity and associated assessment before being commercialized.
纳米技术为各个工业和消费领域提供了独特的属性,已成为全球科学界关注的热点话题。我们的社会已经从纳米技术中受益匪浅,因为已经开发和商业化了许多具有新颖性能和广泛适用性的产品。然而,纳米材料产量和使用量的增加引起了人们对纳米颗粒和纳米材料环境归宿和毒理学影响的关注。研究表明,各种纳米材料可能对生物有危害。在生物群中,植物广泛暴露于释放的纳米材料并对其影响敏感。纳米材料在环境中的积累是一种潜在的威胁,不仅因为它们可能对植物造成潜在损害,还因为纳米颗粒可能进入食物链。尽管有关纳米产品安全性的文献在不断增加,但对于这些材料对包括人类在内的自然物种产生毒性的机制知之甚少。在本文中,我们回顾了与制造的纳米颗粒(例如碳纳米管、金属和金属氧化物纳米颗粒以及某些其他纳米材料)对植物的植物毒性影响相关的文献。纳米颗粒对植物的生理学和形态学产生了多种影响。已知纳米颗粒会影响根结构、种子发芽和细胞代谢。纳米颗粒抑制生长、诱导氧化应激、形态异常并在几种植物物种中产生致突变干扰。纳米颗粒的尺寸、形状和表面涂层在确定其毒性水平方面起着重要作用。当然,剂量、给药途径、分散介质的类型和环境暴露也会影响纳米颗粒对植物的毒性。目前,纳米毒性研究仅处于初始发展阶段,需要进行更多的研究以确定纳米产品对植物系统构成的实际威胁。迄今为止,数据表明,不同的 NPs 引起的植物毒性有很大差异。此外,迄今为止进行的研究主要依赖于显微镜来检测效果。需要进行更多采用现代工具进行的测量和分析的研究。在最急需关于 NPs 的新数据中,有关于制造的 NPs 一旦释放到环境中如何行为以及暴露于它们如何影响植物抗性、代谢途径和植物遗传反应的信息。在本综述中,我们试图收集、呈现和总结植物中纳米颗粒毒性的文献中的最新发现。为了加强分析,我们提出了一种评估 NP 毒性的方案。我们还建议如何解决纳米颗粒产量和释放增加带来的潜在挑战。我们相信并建议,在商业化之前,应针对每个基于纳米材料的产品进行适当的毒性和相关评估。
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