Terakado Shingo, Glass Thomas R, Sasaki Kazuhiro, Ohmura Naoya
Environmental Science Research Laboratory, Central Research Institute of Electric Power Industry.
Anal Sci. 2014;30(3):413-8. doi: 10.2116/analsci.30.413.
A simple new model for estimating the screening performance (false positive and false negative rates) of a given test for a specific sample population is presented. The model is shown to give good results on a test population, and is used to estimate the performance on a sampled population. Using the model developed in conjunction with regulatory requirements and the relative costs of the confirmatory and screening tests allows evaluation of the screening test's utility in terms of cost savings. Testers can use the methods developed to estimate the utility of a screening program using available screening tests with their own sample populations.
提出了一种简单的新模型,用于估计特定样本群体中给定检测的筛查性能(假阳性率和假阴性率)。该模型在测试群体上显示出良好的结果,并用于估计抽样群体的性能。结合监管要求以及确证性检测和筛查检测的相对成本使用所开发的模型,可以从节省成本的角度评估筛查检测的效用。检测人员可以使用所开发的方法,利用可用的筛查检测及其自身的样本群体来估计筛查计划的效用。