• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

腹主动脉瘤破裂的血管内修复对胃肠和肾功能的影响。

The impact of endovascular repair of ruptured abdominal aortic aneurysm on the gastrointestinal and renal function.

作者信息

Makar R R, Badger S A, O'Donnell M E, Soong C V, Lau L L, Young I S, Hannon R J, Lee B

机构信息

Vascular and Endovascular Surgery Unit, Belfast City Hospital, Lisburn Road, Belfast BT9 7AB, UK.

出版信息

Int J Vasc Med. 2014;2014:178323. doi: 10.1155/2014/178323. Epub 2014 Jan 29.

DOI:10.1155/2014/178323
PMID:24616809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3927867/
Abstract

Introduction. Systemic effects of ruptured abdominal aortic aneurysm (rAAA) may be altered by the mode of surgery. This study aimed to determine systemic effects of endovascular aneurysm repair (EVAR) compared to open repair (OR). Patients and Methods. Consecutive patients with rAAA were repaired by OR or EVAR according to computerised tomographic (CT) findings. Renal function was monitored by estimated glomerular filtration rate (eGFR), serum urea and creatinine, and urinary albumin creatinine ratio (ACR). Hepatic function was assessed postoperatively for 5 days. Intestinal function was determined by the paracetamol absorption test. Intestinal permeability was assessed by urinary lactulose/mannitol ratio. Results. 30 rAAA patients were included. Fourteen had eEVAR and sixteen eOR. Serum urea were higher in eOR, while creatinine was similar between groups. Hepatic function showed no intergroup difference. Paracetamol absorption was increased in eEVAR group at day 3 compared to day 1 (P = 0.03), with no similar result in eOR (P = 0.24). Peak lactulose/mannitol ratio was higher in eOR (P = 0.03), with higher urinary L/M ratio in eOR at day 3 (P = 0.02). Clinical intestinal function returned quicker in eEVAR (P = 0.02). Conclusion. EVAR attenuated the organ dysfunction compared to open repair. However, a larger comparative trial would be required to validate this. The clinical trial is registered with reference number EUDRACT: 2013-003373-12.

摘要

引言。腹主动脉瘤破裂（rAAA）的全身效应可能因手术方式而改变。本研究旨在确定与开放修复（OR）相比，血管内动脉瘤修复（EVAR）的全身效应。患者与方法。根据计算机断层扫描（CT）结果，对连续性rAAA患者采用OR或EVAR进行修复。通过估计肾小球滤过率（eGFR）、血清尿素和肌酐以及尿白蛋白肌酐比值（ACR）监测肾功能。术后5天评估肝功能。通过对乙酰氨基酚吸收试验确定肠道功能。通过尿乳果糖/甘露醇比值评估肠道通透性。结果。纳入30例rAAA患者。14例行EVAR，16例行OR。OR组血清尿素较高，而两组间肌酐相似。肝功能无组间差异。与第1天相比，EVAR组在第3天对乙酰氨基酚吸收增加（P = 0.03），OR组无类似结果（P = 0.24）。OR组峰值乳果糖/甘露醇比值较高（P = 0.03），OR组在第3天尿L/M比值较高（P = 0.02）。EVAR组临床肠道功能恢复更快（P = 0.02）。结论。与开放修复相比，EVAR减轻了器官功能障碍。然而，需要更大规模的对比试验来验证这一点。该临床试验已注册，注册号为EUDRACT：2013 - 003373 - 12。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/6590d531d14c/IJVM2014-178323.011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/d0bc1d4c3bbd/IJVM2014-178323.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/4a30046e6ee4/IJVM2014-178323.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/16f881c1e83f/IJVM2014-178323.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/8c587eb7fbbc/IJVM2014-178323.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/26f40af6914c/IJVM2014-178323.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/c888cb630ca2/IJVM2014-178323.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/eb0e543401a7/IJVM2014-178323.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/1daed0c86204/IJVM2014-178323.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/94b3cb2234fc/IJVM2014-178323.009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/2c8102e36124/IJVM2014-178323.010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/6590d531d14c/IJVM2014-178323.011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/d0bc1d4c3bbd/IJVM2014-178323.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/4a30046e6ee4/IJVM2014-178323.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/16f881c1e83f/IJVM2014-178323.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/8c587eb7fbbc/IJVM2014-178323.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/26f40af6914c/IJVM2014-178323.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/c888cb630ca2/IJVM2014-178323.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/eb0e543401a7/IJVM2014-178323.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/1daed0c86204/IJVM2014-178323.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/94b3cb2234fc/IJVM2014-178323.009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/2c8102e36124/IJVM2014-178323.010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb06/3927867/6590d531d14c/IJVM2014-178323.011.jpg

相似文献

1
The impact of endovascular repair of ruptured abdominal aortic aneurysm on the gastrointestinal and renal function.腹主动脉瘤破裂的血管内修复对胃肠和肾功能的影响。
Int J Vasc Med. 2014;2014:178323. doi: 10.1155/2014/178323. Epub 2014 Jan 29.
2
Endograft treatment of ruptured abdominal aortic aneurysms using the Talent aortouniiliac system: an international multicenter study.使用Talent主动脉单髂动脉系统对破裂腹主动脉瘤进行腔内修复治疗：一项国际多中心研究。
J Vasc Surg. 2006 Jun;43(6):1111-1123; discussion 1123. doi: 10.1016/j.jvs.2006.01.035.
3
The inflammatory response to ruptured abdominal aortic aneurysm is altered by endovascular repair.腹主动脉瘤破裂后的炎症反应会因血管内修复而改变。
Int J Vasc Med. 2013;2013:482728. doi: 10.1155/2013/482728. Epub 2013 Dec 2.
4
Improved survival after introduction of an emergency endovascular therapy protocol for ruptured abdominal aortic aneurysms.引入针对破裂腹主动脉瘤的紧急血管内治疗方案后生存率提高。
J Vasc Surg. 2007 Mar;45(3):443-50. doi: 10.1016/j.jvs.2006.11.047. Epub 2007 Jan 25.
5
Emergency endovascular aneurysm repair for ruptured abdominal aortic aneurysms: an institutional experience.破裂腹主动脉瘤的急诊血管内动脉瘤修复术：机构经验
Acta Chir Belg. 2010 May-Jun;110(3):272-4. doi: 10.1080/00015458.2010.11680616.
6
Complete replacement of open repair for ruptured abdominal aortic aneurysms by endovascular aneurysm repair: a two-center 14-year experience.完全采用血管内修复术替代开放手术治疗破裂腹主动脉瘤：14 年两中心经验。
Ann Surg. 2012 Nov;256(5):688-95; discussion 695-6. doi: 10.1097/SLA.0b013e318271cebd.
7
Mid-term outcomes following emergency endovascular aortic aneurysm repair for ruptured abdominal aortic aneurysms.破裂性腹主动脉瘤行急诊血管内修复术后的中期结果。
Eur J Vasc Endovasc Surg. 2012 Apr;43(4):382-5. doi: 10.1016/j.ejvs.2011.12.023. Epub 2012 Jan 18.
8
The effects of abdominal compartment hypertension after open and endovascular repair of a ruptured abdominal aortic aneurysm.腹主动脉瘤破裂开放修复和血管腔内修复术后腹腔间隔室综合征的影响
J Vasc Surg. 2009 Apr;49(4):866-72. doi: 10.1016/j.jvs.2008.11.027.
9
Endovascular treatment for ruptured abdominal aortic aneurysm.腹主动脉瘤破裂的血管内治疗
Cochrane Database Syst Rev. 2007 Jan 24(1):CD005261. doi: 10.1002/14651858.CD005261.pub2.
10
A comparison of renal function between open and endovascular aneurysm repair in patients with baseline chronic renal insufficiency.基线慢性肾功能不全患者开放手术与血管内动脉瘤修复术的肾功能比较。
J Vasc Surg. 2006 Oct;44(4):706-11. doi: 10.1016/j.jvs.2006.05.049. Epub 2006 Aug 23.

引用本文的文献

1
Endovascular repair or open repair for ruptured abdominal aortic aneurysm: a Cochrane systematic review.腹主动脉瘤破裂的血管内修复或开放修复：一项Cochrane系统评价
BMJ Open. 2016 Feb 12;6(2):e008391. doi: 10.1136/bmjopen-2015-008391.

本文引用的文献

1
Retroperitoneal approach to abdominal aortic aneurysm repair preserves splanchnic perfusion as measured by gastric tonometry.经腹膜后途径行腹主动脉瘤修复术可维持经胃张力测定法所测量的内脏灌注。
Ann Vasc Surg. 2010 Apr;24(3):321-7. doi: 10.1016/j.avsg.2009.06.003. Epub 2009 Sep 11.
2
The effects of abdominal compartment hypertension after open and endovascular repair of a ruptured abdominal aortic aneurysm.腹主动脉瘤破裂开放修复和血管腔内修复术后腹腔间隔室综合征的影响
J Vasc Surg. 2009 Apr;49(4):866-72. doi: 10.1016/j.jvs.2008.11.027.
3
A meta-analysis of 21,178 patients undergoing open or endovascular repair of abdominal aortic aneurysm.
一项对21178例接受腹主动脉瘤开放修复或血管腔内修复患者的荟萃分析。
Br J Surg. 2008 Jun;95(6):677-84. doi: 10.1002/bjs.6240.
4
Endovascular vs open repair of acute abdominal aortic aneurysms--a systematic review and meta-analysis.急性腹主动脉瘤的血管内修复与开放修复——一项系统评价和荟萃分析
J Vasc Surg. 2008 Jul;48(1):227-36. doi: 10.1016/j.jvs.2007.11.028. Epub 2008 Feb 1.
5
Endovascular ruptured abdominal aortic aneurysm repair (EVRAR): a systematic review.血管内破裂腹主动脉瘤修复术（EVRAR）：一项系统评价
Eur J Vasc Endovasc Surg. 2007 Dec;34(6):673-81. doi: 10.1016/j.ejvs.2007.06.004. Epub 2007 Aug 27.
6
Transperitoneal approach should be considered for suspected ruptured abdominal aortic aneurysms.
Ann Vasc Surg. 2007 Mar;21(2):129-32. doi: 10.1016/j.avsg.2006.10.019.
7
Postoperative nausea and vomiting.术后恶心呕吐
Auton Neurosci. 2006 Oct 30;129(1-2):86-91. doi: 10.1016/j.autneu.2006.07.017. Epub 2006 Aug 30.
8
A randomised trial of endovascular and open surgery for ruptured abdominal aortic aneurysm - results of a pilot study and lessons learned for future studies.腹主动脉瘤破裂的血管内手术与开放手术随机试验——一项初步研究的结果及对未来研究的经验教训
Eur J Vasc Endovasc Surg. 2006 Nov;32(5):506-13; discussion 514-5. doi: 10.1016/j.ejvs.2006.05.016. Epub 2006 Aug 1.
9
Review of the pathophysiology and management of postoperative ileus.术后肠梗阻的病理生理学及管理综述。
World J Surg. 2006 Aug;30(8):1382-91. doi: 10.1007/s00268-005-0613-9.
10
Endograft treatment of ruptured abdominal aortic aneurysms using the Talent aortouniiliac system: an international multicenter study.使用Talent主动脉单髂动脉系统对破裂腹主动脉瘤进行腔内修复治疗：一项国际多中心研究。
J Vasc Surg. 2006 Jun;43(6):1111-1123; discussion 1123. doi: 10.1016/j.jvs.2006.01.035.