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老年髋部骨折患者抗凝管理算法——外科医生节约用血

Algorithm for anticoagulation management in geriatric hip fracture patients--Surgeons save Blood.

作者信息

Wendl-Soeldner M A, Moll C W I, Kammerlander C, Gosch M, Roth T

机构信息

Department for Trauma Surgery, Medical University of Innsbruck, Anichstr. 35, 6020, Innsbruck, Austria.

出版信息

Z Gerontol Geriatr. 2014 Feb;47(2):95-104. doi: 10.1007/s00391-013-0595-4.

DOI:10.1007/s00391-013-0595-4
PMID:24619040
Abstract

During the past decades, the number of hip fractures has been increasing steadily. Perioperative thromboprophylaxis has become a routine aspect in the care of geriatric hip fracture patients. In addition, a large proportion of these patients are already anticoagulated because of internistic comorbidities before they sustained the hip fracture. Although the management of preexisting anticoagulation in both orthopedic elective and emergency procedures is well reported, proximal femoral fractures are classified as "acute" and therefore represent neither of these two categories. In this study, we review the different options of handling preexisting anticoagulation and antiaggregation as well as perioperative thromboprophylaxis. The Innsbruck Algorithm for the management of anticoagulation in geriatric hip fracture patients suggests how perioperative bleeding risk can be minimized, while still addressing the underlying disease.

摘要

在过去几十年中,髋部骨折的数量一直在稳步增加。围手术期血栓预防已成为老年髋部骨折患者护理中的常规内容。此外,这些患者中有很大一部分在发生髋部骨折之前,由于内科合并症已经在接受抗凝治疗。尽管对于骨科择期手术和急诊手术中已有抗凝治疗的管理已有充分报道,但股骨近端骨折被归类为“急性”骨折,因此不属于这两类中的任何一种。在本研究中,我们回顾了处理已有抗凝和抗聚集治疗以及围手术期血栓预防的不同选择。因斯布鲁克老年髋部骨折患者抗凝管理算法表明了如何在治疗基础疾病的同时,将围手术期出血风险降至最低。

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Algorithm for anticoagulation management in geriatric hip fracture patients--Surgeons save Blood.老年髋部骨折患者抗凝管理算法——外科医生节约用血
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2
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Development and initial evaluation of a point-of-care educational app on medical topics in orthogeriatrics.老年骨科医学主题即时医疗教育应用程序的开发与初步评估
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[Proximal femoral fractures in the elderly].

本文引用的文献

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Comparison of different warfarin reversal protocols on surgical delay and complication rate in hip fracture patients.不同华法林逆转方案对髋部骨折患者手术延迟和并发症发生率的比较。
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[老年人股骨近端骨折]
Z Gerontol Geriatr. 2015 Oct;48(7):647-59; quiz 660-1. doi: 10.1007/s00391-015-0939-3.
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Dabigatran effects on the international normalized ratio, activated partial thromboplastin time, thrombin time, and fibrinogen: a multicenter, in vitro study.达比加群对国际标准化比值、活化部分凝血活酶时间、凝血酶时间和纤维蛋白原的影响:一项多中心、体外研究。
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Should more patients continue aspirin therapy perioperatively?: clinical impact of aspirin withdrawal syndrome.更多患者应继续围手术期阿司匹林治疗吗?:阿司匹林停药综合征的临床影响。
Ann Surg. 2012 May;255(5):811-9. doi: 10.1097/SLA.0b013e318250504e.
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Antiplatelet drugs: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.抗血小板药物:抗血栓治疗和血栓预防,第 9 版:美国胸科医师学院循证临床实践指南。
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Perioperative management of antithrombotic therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.抗栓治疗的围手术期管理:抗栓治疗与血栓预防,第 9 版:美国胸科医师学会循证临床实践指南。
Chest. 2012 Feb;141(2 Suppl):e326S-e350S. doi: 10.1378/chest.11-2298.