Vargová Lenka, Horácková Ladislava, Nemecková Alena, Krupa Petr, Mensíková Miroslava
Anthropol Anz. 2013;70(4):385-405. doi: 10.1127/0003-5548/2013/0343.
Symptoms signs of benign and malignant tumors were observed during paleopathological analysis of skeletal remains from the city of Brno in the Czech Republic. Approximately 1,200 skeletons were examined from two Modern era archaeology sites: the Malá Nová ulice (Little New Street) cemetery and the cemetery of the Nemocnice Milosrdných bratrí (Merciful Brothers' Hospital). Osteomas, usually located on the flat bones of the cranial vault, were the most frequent skeletal pathology. Symptoms signs of malignant tumors were observed in three cases. In one case lytic foci caused by the metastases of a malignant tumor in the soft tissue was observed. Traces of myeloma multiplex were found in two individuals. Living conditions in that period, and possible carcinogenic environmental influences were assessed for the general population of Brno. This report contributes to a better understanding of the historical development of cancers and the clarification of possible causes for their modern increase of incidence.
在对捷克布尔诺市出土的骨骼遗骸进行古病理学分析期间，观察了良性和恶性肿瘤的症状体征。从两个现代考古遗址中检查了约1200具骨骼：小新街墓地和仁慈兄弟医院墓地。骨瘤通常位于颅顶的扁骨上，是最常见的骨骼病理情况。观察到3例恶性肿瘤的症状体征。其中1例观察到软组织中恶性肿瘤转移引起的溶骨病灶。在2个人中发现了多发性骨髓瘤的痕迹。对布尔诺市普通人群那个时期的生活条件以及可能的致癌环境影响进行了评估。本报告有助于更好地了解癌症的历史发展，并阐明其现代发病率上升的可能原因。
