Di Piazza Mariaconcetta, Bonomo Vito, Gandolfo Caterina, Stabile Amerigo, Novo Salvatore
Recenti Prog Med. 2014 Feb;105(2):63-7. doi: 10.1701/1417.15698.
Degenerative aortic stenosis is the most common form of heart valve disease in developed countries and predominantly affects the elderly. Aortic valve replacement (AVR) has been the gold standard, but recently, transcatheter aortic valve implantation has emerged as an effective therapeutic alternative to conventional AVR for high-risk patients. This review analyzed the literature about AVR, with the objective of evaluating the outcomes of transcatheter aortic valve implantation in patients who are not eligible for surgery showing an improvement in quality of life and middle-term outcomes. The crucial point is the lack of studies with long-term follow-up that could give therapeutic importance to percutaneous valve replacement.
退行性主动脉瓣狭窄是发达国家最常见的心脏瓣膜病形式，主要影响老年人。主动脉瓣置换术（AVR）一直是金标准，但最近，经导管主动脉瓣植入术已成为高危患者传统AVR的有效治疗替代方案。本综述分析了有关AVR的文献，目的是评估经导管主动脉瓣植入术在不符合手术条件的患者中的疗效，这些患者的生活质量和中期预后有所改善。关键问题是缺乏长期随访研究，这些研究可能会赋予经皮瓣膜置换术治疗重要性。
