Grazi Marco, Rubino Mara, Milazzo Valentina, Cabiati Angelo
Recenti Prog Med. 2014 Feb;105(2):68-72. doi: 10.1701/1417.15699.
Mild therapeutic hypothermia improves neurological outcomes after cardiac arrest by preserving brain function. It is currently under discussion the possibility that hypothermia may also provide a protective effect on cardiac function, in particular, by reducing the infarct size in patients with acute myocardial infarction complicated by cardiac arrest. Despite encouraging experimental and clinical data obtained so far may suggest a potential future indication in this population, routine use of therapeutic hypothermia in acute myocardial infarction patients needs further investigation and it is not currently recommended.
轻度治疗性低温通过保护脑功能改善心脏骤停后的神经学转归。目前正在讨论低温是否也可能对心脏功能提供保护作用,特别是通过减小急性心肌梗死合并心脏骤停患者的梗死面积。尽管迄今为止获得的令人鼓舞的实验和临床数据可能提示该人群未来有潜在适应证,但急性心肌梗死患者中治疗性低温的常规应用仍需进一步研究,目前不推荐使用。