Hamaya K, Doi K, Yoshizawa S, Motoi M
Anatomic Pathology, Okayama Saiseikai General Hospital.
Gan No Rinsho. 1988 Nov;34(14):1956-60.
An immuno-histological study of metastatic adenocarcinoma has revealed the following results. Metastatic adenocarcinomas of the lymph-node of pulmonary and colonic origin were positive for CEA and negative for lysozymes, and those from gastric, pancreatic, and gallbladder tumors were positive CEA and lysozymes, and those from gastric and pancreatic tumors were positive for the secretory component. The prostate specific antigen was exclusively positive for metastatic prostatic adenocarcinoma with a low frequency and prostate acid phosphatase had many false positive results. Thyroglobulin was found to be positive only to colloid. Lactalbumin showed no specificity to metastatic breast adenocarcinoma. For achieving the final diagnosis of a primary tumor, its location in lymph nodes, the clinical history and the results of other examinations must also be taken into consideration.
一项转移性腺癌的免疫组织学研究得出了以下结果。肺和结肠来源的淋巴结转移性腺癌癌胚抗原（CEA）呈阳性，溶菌酶呈阴性；胃、胰腺和胆囊肿瘤来源的转移性腺癌CEA和溶菌酶均呈阳性，胃和胰腺肿瘤来源的转移性腺癌分泌成分呈阳性。前列腺特异性抗原仅在少数转移性前列腺腺癌中呈阳性，前列腺酸性磷酸酶有许多假阳性结果。甲状腺球蛋白仅对胶体呈阳性。乳白蛋白对转移性乳腺腺癌无特异性。为了最终诊断原发性肿瘤，还必须考虑其在淋巴结中的位置、临床病史和其他检查结果。
