Pedro Abizanda Soler, Hospital Perpetuo Socorro, C/ Seminario 4, 02006 Albacete, Spain, Tel.: +34967597651, Fax: +34967597635, Email:
J Nutr Health Aging. 2014 Mar;18(3):270-6. doi: 10.1007/s12603-013-0388-x.
To analyze if body mass index (BMI) and waist circumference (WC) as measures of nutritional status, and the Mini Nutritional Assessment Short Form (MNA-SF) as a nutritional risk measure are associated with increased risk of incident disability in basic activities of daily living (BADL) in a population based cohort of Spanish older adults.
Concurrent cohort study.
Albacete City, Spain.
678 subjects over age 70 from the FRADEA Study (Frailty and Dependence in Albacete).
BMI, WC and MNA-SF were recorded at the basal visit of the FRADEA Study. Incident disability in BADL was defined as loss of the ability to perform bathing, grooming, dressing, toilet use, or feeding from basal to follow-up visit, using the Barthel index. The association between nutritional status and nutritional risk with incident BADL disability was determined by Kaplan-Meier analysis and logistic regression adjusted for age, sex, basal function, comorbidity, cognitive decline, depression risk and frailty status.
Each point less of MNA-SF (OR 1.17, 95%CI 1.04-1.31) and MNA-SF<14 (OR 2.33, 95%CI 1.39-3.89), but not MNA-SF<12 (OR 1.47, 95%CI 0.89-2.42) had a greater adjusted risk of incident disability in BADL. Neither BMI (OR 1.02, 95%CI 0.97-1.06) nor WC (OR 1.01, 95%CI 0.99-1.03) were associated. Weight loss (OR 1.75, 95%CI 1.08-2.83) and mobility impairment (OR 3.35, 95%CI 1.67-6.73) remained as adjusted predictors of incident BADL disability, while anorexia almost reached the significance (OR 1.65, 95%CI 0.94-2.87).
Nutritional risk measured with the MNA-SF is associated with incident disability in BADL in older adults, while nutritional status measured with BMI or WC is not.
分析体重指数（BMI）和腰围（WC）作为营养状况的衡量标准，以及迷你营养评估简表（MNA-SF）作为营养风险测量指标，是否与西班牙老年人群中基本日常生活活动（BADL）的新发残疾风险增加有关。
同期队列研究。
西班牙阿尔瓦塞特市。
来自 FRADEA 研究（阿尔瓦塞特衰弱和依赖）的 678 名 70 岁以上的受试者。
在 FRADEA 研究的基础访问时记录 BMI、WC 和 MNA-SF。BADL 新发残疾定义为从基础随访访视时丧失洗澡、梳妆、穿衣、使用厕所或进食的能力，使用巴氏量表。通过 Kaplan-Meier 分析和调整年龄、性别、基础功能、合并症、认知衰退、抑郁风险和虚弱状态后的 logistic 回归，确定营养状况和营养风险与 BADL 新发残疾之间的关联。
MNA-SF 每减少 1 分（OR 1.17，95%CI 1.04-1.31）和 MNA-SF<14（OR 2.33，95%CI 1.39-3.89）的调整后 BADL 新发残疾风险更高，但 MNA-SF<12（OR 1.47，95%CI 0.89-2.42）则不然。BMI（OR 1.02，95%CI 0.97-1.06）或 WC（OR 1.01，95%CI 0.99-1.03）均与 BADL 无关。体重减轻（OR 1.75，95%CI 1.08-2.83）和行动障碍（OR 3.35，95%CI 1.67-6.73）仍然是 BADL 新发残疾的调整预测因素，而厌食症几乎达到显著性（OR 1.65，95%CI 0.94-2.87）。
使用 MNA-SF 测量的营养风险与老年人 BADL 的新发残疾有关，而 BMI 或 WC 测量的营养状况则没有。
