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[分娩期女性氨苄西林预防用药后过敏反应的治疗]

[Treatment of anaphylaxis after ampicillin prophylaxis in a woman in labour].

作者信息

Stryhn Julie, Weber Tom

机构信息

Urologisk Afdeling, Næstved Sygehus, Ringstedgade 61, 4700 Næstved.

出版信息

Ugeskr Laeger. 2013 Oct 21;175(43):2566-8.

Abstract

A primipara developed anaphylaxis during labour due to intravenous (i.v.) administration of ampicillin given prophylactic against group B streptococcal infection. Initially, she was treated with oxygen, i.v. fluids, antihistamine and a slight left-side position. Fifteen minutes later she was given 0.5 mg adrenaline i.v. due to persistent foetal bradycardia (60-90 bpm). Seven minutes later the foetal heart rate could not be detected. By acute caesarean section a child with Apgar score 1/1 was delivered and resuscitated. Cord arterial blood-pH was 6.97, base excess -9.2 mmol/l and lactate level 12.5 mmol/l. One month later the child appeared normal.

摘要

一名初产妇在分娩期间因静脉注射氨苄西林预防B族链球菌感染而发生过敏反应。起初,她接受了吸氧、静脉输液、抗组胺药治疗,并采取了轻微左侧卧位。15分钟后,由于持续性胎儿心动过缓(60-90次/分),她接受了静脉注射0.5毫克肾上腺素。7分钟后,胎儿心率无法检测到。通过紧急剖宫产分娩出一名阿氏评分1/1的婴儿并进行了复苏。脐动脉血pH值为6.97,碱剩余为-9.2毫摩尔/升,乳酸水平为12.5毫摩尔/升。一个月后,婴儿看起来正常。

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