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[选择性5-羟色胺再摄取抑制剂与妊娠]

[Selective serotonin reuptake inhibitors and pregnancy].

作者信息

Hassanzadeh Tahmineh, Pedersen Lars Henning, Videbech Poul

机构信息

Bellisvej 11, 8464 Galten.

出版信息

Ugeskr Laeger. 2014 Feb 3;176(3):236-9.

Abstract

Selective serotonin reuptake inhibitors (SSRI) is the most common pharmacological treatment for depression during pregnancy. In recent years it has been under suspicion of causing spontaneous abortion, cardiac malformation, preterm birth, low birthweight, persistent pulmonary hypertension and neonatal withdrawal syndrome in the newborn exposed to SSRI. But the risks of SSRI side effects are low compared to background population. Non-pharmacological treatment methods should also be considered while treating pregnant women with depression. This paper describes the present state of knowledge about the potential complications associated with the use of SSRI during pregnancy and points at treatment recommendations to the physician.

摘要

选择性5-羟色胺再摄取抑制剂(SSRI)是孕期抑郁症最常用的药物治疗方法。近年来,它一直被怀疑会导致接触SSRI的新生儿出现自然流产、心脏畸形、早产、低出生体重、持续性肺动脉高压和新生儿戒断综合征。但与一般人群相比,SSRI副作用的风险较低。在治疗患有抑郁症的孕妇时,也应考虑非药物治疗方法。本文描述了孕期使用SSRI相关潜在并发症的现有知识状况,并为医生提供了治疗建议。

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