克莱恩-莱文综合征：一例病例报告及文献综述
Kleine-Levin syndrome: a case report and review of literature.
作者信息
Das Sourav, Gupta Ravi, Dhyani Mohan, Raghuvanshi Shailendra
机构信息
Department of Psychiatry and Sleep Clinic, Himalayan Institute of Medical Sciences, Doiwala, Dehradun, India.
Department of Psychiatry and Sleep Clinic, Himalayan Institute of Medical Sciences, Doiwala, Dehradun, India.
出版信息
Pediatr Neurol. 2014 Apr;50(4):411-6. doi: 10.1016/j.pediatrneurol.2014.01.003. Epub 2014 Jan 6.
BACKGROUND
Kleine-Levin syndrome presents with recurrent hypersomnia along with a number of other neuropsychiatric features, of which hyperorality has not been described frequently.
METHOD
We report a male adolescent who presented with recurrent hypersomnia, hypersexuality, and hyperorality. Magnetic resonance imaging of the brain and overnight polysomnography followed by a multiple sleep latency tests were ordered. Excessive daytime sleepiness was assessed with the Epworth Sleepiness Scale.
RESULTS
Magnetic resonance imaging of the brain did not reveal any abnormality. Overnight video-synchronized polysomnography and multiple sleep latency tests ruled out narcolepsy. Epworth Sleepiness Scale score at baseline was 22. He was prescribed lithium carbonate 300 mg twice a day. The symptoms improved within a week after starting lithium carbonate therapy.
CONCLUSION
Kleine-Levin syndrome may present with hyperorality, and our patient responded well to lithium carbonate therapy.
背景
克莱恩-莱文综合征表现为反复性嗜睡以及一系列其他神经精神症状，其中口欲亢进并不常见。
方法
我们报告一名男性青少年，他出现反复性嗜睡、性欲亢进和口欲亢进。安排了脑部磁共振成像、夜间多导睡眠图检查，随后进行多次睡眠潜伏期测试。使用爱泼华嗜睡量表评估日间过度嗜睡情况。
结果
脑部磁共振成像未发现任何异常。夜间视频同步多导睡眠图和多次睡眠潜伏期测试排除了发作性睡病。基线时爱泼华嗜睡量表评分为22分。给他开了碳酸锂，每日两次，每次300毫克。开始碳酸锂治疗后一周内症状有所改善。
结论
克莱恩-莱文综合征可能表现为口欲亢进，我们的患者对碳酸锂治疗反应良好。
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