Mathew Mathew T, Kerwell Shelley, Lundberg Hannah J, Sukotjo Cortino, Mercuri Louis G
Department of Orthopedic Surgery, Rush University Medical Center, Institute of Biomaterials, Tribocorrosion and Nanomedicine, Chicago, IL, United States.
University of Illinois Chicago, Department of Bioengineering, Institute of Biomaterials, Tribocorrosion and Nanomedicine, Chicago, IL, United States.
Br J Oral Maxillofac Surg. 2014 May;52(5):396-400. doi: 10.1016/j.bjoms.2014.02.010. Epub 2014 Mar 14.
The release of metal ions or material particles, or both, into tissues that surround implanted medical or dental devices can create postimplantation complications. These rare but disturbing events are mainly caused by the mechanical movements of the components of the implant against each other, coupled with the influences of local biochemical and electrochemical factors. Mechanical movement of the components of implants against each other results in friction and wear, the study of which is called tribology. The tribology of an implanted device depends on the patient's activity and is affected by variables such as load, frequency, and the surface properties of the components of the implant that are in contact. Local biochemical and electrochemical factors include the ambient pH, and concentrations of protein and oxygen. The effect on local tissues and extracellular fluid can produce biochemical or electrochemical responses to the implant material in the surrounding solution, which is termed corrosion. The combined effect of these mechanical, biochemical, and electrochemical factors is known as tribocorrosion. In this paper we will provide a brief overview of the basic principles of tribocorrosion, and its current status and future perspectives, to create awareness and interest, and to inspire research into its effects on implantable devices in oral and maxillofacial surgery. The information garnered from such investigations, appropriately applied, will not only improve present devices but also will lead to the development of superior ones, ultimately improving care and outcomes for patients.
金属离子或材料颗粒,或两者同时释放到植入的医疗或牙科设备周围的组织中,可能会引发植入后的并发症。这些罕见但令人不安的事件主要是由植入物部件之间的机械运动,以及局部生化和电化学因素的影响共同导致的。植入物部件之间的机械运动导致摩擦和磨损,对其的研究称为摩擦学。植入设备的摩擦学取决于患者的活动,并受诸如负载、频率以及相互接触的植入物部件的表面特性等变量的影响。局部生化和电化学因素包括周围环境的pH值、蛋白质浓度和氧气浓度。对局部组织和细胞外液的影响会在周围溶液中对植入材料产生生化或电化学反应,这被称为腐蚀。这些机械、生化和电化学因素的综合作用被称为摩擦腐蚀。在本文中,我们将简要概述摩擦腐蚀的基本原理、其现状和未来展望,以提高认识和激发兴趣,并推动对其在口腔颌面外科植入设备中影响的研究。从这类研究中获取的信息,若得到恰当应用,不仅会改进现有设备,还将促使更优质设备的研发,最终改善患者的护理和治疗效果。