57钴-博来霉素闪烁扫描术在肺癌脑转移检测中的应用

57Co-bleomycin scintigraphy in the detection of brain metastases of lung cancer.

作者信息

Nieweg O, Piers D A, Beekhuis H

机构信息

Dept. of Surgery, University Hospital Groningen, The Netherlands.

出版信息

Clin Neurol Neurosurg. 1988;90(2):109-11. doi: 10.1016/s0303-8467(88)80027-1.

DOI:10.1016/s0303-8467(88)80027-1

PMID:2463129

Abstract

57Co-bleomycin scintigraphy was used to detect brain metastases in 46 patients with proven lung cancer and neurological symptoms that could be caused by brain metastases. Scintigraphy was true positive in 19 patients and true negative in 27. In 44 patients without neurological symptoms 57Co-bleomycin scintigraphy was performed to detect silent brain metastases at the time the diagnosis of lung cancer was established. Scintigraphy was false negative in one of these patients and true negative in 43. It is concluded that 57Co-bleomycin scintigraphy is a reliable method to visualize brain metastases in lung cancer patients with neurological symptoms. In our patients it was not useful to detect silent brain metastases of lung cancer.

摘要

采用57钴-博来霉素闪烁扫描法对46例已确诊肺癌且伴有可能由脑转移引起的神经症状的患者进行脑转移检测。闪烁扫描法在19例患者中为真阳性，27例为真阴性。对44例无神经症状的患者在确诊肺癌时进行57钴-博来霉素闪烁扫描法以检测隐匿性脑转移。其中1例患者闪烁扫描法为假阴性，43例为真阴性。结论是57钴-博来霉素闪烁扫描法是检测伴有神经症状的肺癌患者脑转移的可靠方法。在我们的患者中，该方法对检测肺癌隐匿性脑转移并无用处。