Sit Yan Kit, Lui Tun Hing
Department of Orthopaedics and Traumatology, North District Hospital, New Territories, Hong Kong SAR.
BMJ Case Rep. 2014 Mar 14;2014:bcr2013201269. doi: 10.1136/bcr-2013-201269.
Adefovir/tenofovir are commonly used antiviral agents in the treatment of chronic hepatitis B infection (CHB). We report a case of CHB-related cirrhosis presenting with sequential femoral neck fractures. Operative reduction and fixation was performed. Laboratory result and imaging was consistent with hypophosphataemic osteomalacia. He had bilateral femoral neck non-union and presented with a new left side subtrochanteric femoral fracture. Corrective osteotomy and cephalomedullary fixation was performed. The fractures healed in 6 months after correction of the hypophosphataemia.
阿德福韦/替诺福韦是治疗慢性乙型肝炎感染（CHB）常用的抗病毒药物。我们报告一例CHB相关肝硬化患者，先后出现股骨颈骨折。进行了手术复位和固定。实验室检查结果和影像学表现与低磷性骨软化症相符。患者双侧股骨颈骨不连，并出现左侧新的转子下股骨骨折。进行了截骨矫正和髓内钉固定。在纠正低磷血症后6个月骨折愈合。
