Okimoto Tamio, Horimasu Yasushi, Hamaguchi Shunichi, Sutani Akihisa, Amano Chika, Harada Yuji, Maruyama Riruke, Miyamoto Nobuhiro, Kishimoto Koji, Isobe Takeshi
Division of Medical Oncology and Respiratory Medicine, Department of Internal Medicine, Shimane University Faculty of Medicine, Japan.
Intern Med. 2014;53(6):617-21. doi: 10.2169/internalmedicine.53.1657.
A 79-year-old woman was admitted to our hospital for an investigation of a large 13-cm tumor in the chest and treatment for dyspnea in January 2010. The tumor had been observed on chest X-rays since 1992. It had measured 7 cm in 2008, then started to grow rapidly. Further investigations revealed that it was a malignant solitary fibrous tumor that was strongly suspected to have transformed from a benign to malignant state. Resection was not possible, and the patient died one month later. Benign solitary fibrous tumors of the pleura may become malignant during long-term follow-up. All suspected or proven solitary fibrous tumors of the pleura should be resected.