Sun Min, Feng Juanjuan, Luo Chuannan, Liu Xia, Jiang Shengxiang
Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong (University of Jinan), School of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022, China.
Anal Bioanal Chem. 2014 Apr;406(11):2651-8. doi: 10.1007/s00216-014-7680-4. Epub 2014 Mar 16.
A novel stationary phase based on quinolinium ionic liquid-modified silica was prepared and evaluated for high-performance liquid chromatography. The stationary phase was investigated via normal-phase (NP), reversed-phase (RP), and anion-exchange (AE) chromatographic modes, respectively. Polycyclic aromatic hydrocarbons, phthalates, parabens, phenols, anilines, and inorganic anions were used as model analytes in chromatographic separation. Using the newly established column, organic compounds were separated successfully by both NP and RP modes, and inorganic anions were also separated completely by AE mode. The obtained results indicated that the stationary phase could be applied in different chromatographic modes, with multiple-interaction mechanism including van der Waals forces (dipole-dipole, dipole-induced dipole interactions), hydrophobic, π-π stacking, electrostatic forces, hydrogen bonding, anion-exchange interactions, and so on. The column packed with the stationary phase was applied to analyze phthalates and parabens in hexane extracts of plastics. Tap water and bottled water were also analyzed by the column, and nitrate was detected as 20.1 and 13.8 mg L(-1), respectively. The results illustrated that the stationary phase was potential in practical applications.
制备了一种基于喹啉鎓离子液体修饰硅胶的新型固定相，并对其进行了高效液相色谱评价。分别通过正相（NP）、反相（RP）和阴离子交换（AE）色谱模式对该固定相进行了研究。多环芳烃、邻苯二甲酸酯、对羟基苯甲酸酯、酚类、苯胺类和无机阴离子被用作色谱分离中的模型分析物。使用新建立的色谱柱，有机化合物在NP和RP模式下均成功分离，无机阴离子在AE模式下也完全分离。所得结果表明，该固定相可应用于不同的色谱模式，具有多种相互作用机制，包括范德华力（偶极-偶极、偶极-诱导偶极相互作用）、疏水作用、π-π堆积、静电力、氢键、阴离子交换相互作用等。填充有该固定相的色谱柱用于分析塑料己烷提取物中的邻苯二甲酸酯和对羟基苯甲酸酯。该色谱柱还对自来水和瓶装水进行了分析，检测到硝酸盐含量分别为20.1和13.8 mg L(-1)。结果表明该固定相在实际应用中具有潜力。
