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[眼外肌的纤维蛋白黏合。在兔子身上的实验应用]

[Fibrin gluing of the extraocular eye muscles. Experimental use in the rabbit].

作者信息

Aichmair M W, Aichmair H, Lintner F

机构信息

II. Univ.-Augenklinik Wien.

出版信息

Klin Monbl Augenheilkd. 1988 Nov;193(5):499-503. doi: 10.1055/s-2008-1050289.

Abstract

An experimental animal study was conducted to determine whether fibrin glue could be used in strabismus surgery (recession, resection, and muscular neurotization). Fibrin glue was used in place of some or all of the commonly used 7-0 Vicryl sutures. In order to evaluate the adhesion of the fibrin glue the rabbits' eyes were enucleated 10-67 days after surgery, fixed in 8% formalin solution and then histologically examined. In the recession and resection specimens a solid joint between muscles and sclera was found, without any significant scar formation or atrophy of the muscles. The muscular neurotization specimens also exhibited a firm connection between the two muscles, with no abnormal loss of muscle fibers by cicatrization or atrophy. In none of the cases did the conjunctiva show any tendency to conglutination. In view of the simplicity of the fibrin gluing technique and the uniform bonding effect, application in human patients is recommended.

摘要

进行了一项实验动物研究,以确定纤维蛋白胶是否可用于斜视手术(后徙术、切除术和肌肉神经移植术)。使用纤维蛋白胶替代部分或全部常用的7-0薇乔缝线。为了评估纤维蛋白胶的黏附力,在术后10-67天摘除兔眼,固定于8%福尔马林溶液中,然后进行组织学检查。在后徙术和切除术标本中,发现肌肉与巩膜之间形成了牢固的连接,没有任何明显的瘢痕形成或肌肉萎缩。肌肉神经移植术标本中两块肌肉之间也显示出牢固的连接,没有因瘢痕形成或萎缩导致的肌纤维异常丢失。在所有病例中,结膜均无粘连倾向。鉴于纤维蛋白胶黏合技术简单且黏合效果均匀,建议应用于人类患者。

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