Li Na, Peng Xiu-Jun, Fan Zheng-Jun
Department of Ophthalmology, Navy General Hospital of Chinese PLA, Beijing 100048, China.
Int J Ophthalmol. 2014 Feb 18;7(1):157-62. doi: 10.3980/j.issn.2222-3959.2014.01.29. eCollection 2014.
As a photochemical reaction that can stiffen the cornea, corneal collagen cross-linking (CXL) is the only promising method of preventing the progress of keratectasia, such as keratoconus and secondary ectasia following refractive surgery. The aim of CXL is to stabilize the underlying condition, with a small chance of visual improvement. Combining CXL with refractive surgery targeting both stabilization and reshaping of the corneal tissue for visual function improvement is a good treatment option. This review aims to provide a comprehensive and unbiased summary of the published research regarding combined CXL and refractive surgery, including measures and results, to help elucidate the future direction of CXL.
作为一种可使角膜变硬的光化学反应,角膜胶原交联(CXL)是预防圆锥角膜和屈光手术后继发性扩张等角膜扩张进展的唯一有前景的方法。CXL的目的是稳定潜在病情,视力改善的可能性较小。将CXL与针对角膜组织稳定和重塑以改善视觉功能的屈光手术相结合是一种很好的治疗选择。本综述旨在对已发表的关于CXL与屈光手术联合应用的研究进行全面且无偏见的总结,包括措施和结果,以帮助阐明CXL的未来发展方向。