Palmer Matthew J, Nixon Rosemary
Occupational Dermatology Research and Education Centre, Skin and Cancer Foundation, Melbourne, Victoria, Australia.
Australas J Dermatol. 2015 Feb;56(1):56-8. doi: 10.1111/ajd.12160. Epub 2014 Mar 17.
Polysensitisation refers to reactivity to three or more allergens on epicutaneous patch testing, and is likely to affect a distinct subgroup of individuals with allergic contact dermatitis (ACD). Methylisothiazolinone (MIT) is an increasingly prevalent allergen, recently having been described as occurring in epidemic proportions. We report a patient with ACD to 12 allergens, including MIT, and discuss the implications of polysensitisation and the likely need for repeat patch testing in such patients if they subsequently re-present with dermatitis.
多致敏现象是指在皮肤斑贴试验中对三种或更多变应原产生反应，这可能影响过敏性接触性皮炎（ACD）患者中的一个独特亚组。甲基异噻唑啉酮（MIT）是一种日益常见的变应原，最近被描述为呈流行比例出现。我们报告了一名对包括MIT在内的12种变应原发生ACD的患者，并讨论了多致敏现象的影响以及此类患者随后再次出现皮炎时可能需要重复进行斑贴试验的情况。
