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哪种患者最有可能从频率应答式起搏器中获益?

Which patient is most likely to benefit from a rate responsive pacemaker?

作者信息

Heinz M, Wörl H H, Alt E, Theres H, Blömer H

机构信息

I. Medical Clinic, Technical University of Munich, FRG.

出版信息

Pacing Clin Electrophysiol. 1988 Nov;11(11 Pt 2):1834-9. doi: 10.1111/j.1540-8159.1988.tb06317.x.

DOI:10.1111/j.1540-8159.1988.tb06317.x
PMID:2463555
Abstract

In order to provide information about indications for rate responsive pacing, we examined the exercise capacity of a typical collective of pacemaker patients. One hundred seven patients participated in the study, 50/107 (46.8%) suffered from sick sinus syndrome, 37/107 (34.6%) showed complete AV block, 12/107 (11.2%) had bradyarrhythmia and 8/107 (7.4%) had other diseases. All patients underwent treadmill exercise with increasing workloads up to the individual's maximum workload. We monitored heart rate, respiratory rate, workload, the subjective perception of stress according to the Borg scale, and the reason for the termination of exercise. Calculation of oxygen uptake was done according to an equation given by Givoni. During the tests, all implanted pacemakers have been programmed to VVI 70 mode. We found that all pacemaker patients showed a reduction of their exercise capacity compared to the age-related normal values. Particularly in patients with AV block or bradyarrhythmia, the maximum achievable workload often did not even reach levels of everyday activities such as going upstairs; patients with sick sinus syndrome showed slightly better exercise capability, probably due to the higher increase of average heart rate. Despite objective differences of maximum workload, all patients had the same subjective perception at the end of the tests; the course of respiratory rate indicated that all persons finished the tests in the range of individual maximum exercise capacity.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

为了提供有关频率应答性起搏适应证的信息,我们研究了一组典型起搏器患者的运动能力。107例患者参与了该研究,其中50/107(46.8%)患有病态窦房结综合征,37/107(34.6%)表现为完全性房室传导阻滞,12/107(11.2%)有缓慢性心律失常,8/107(7.4%)患有其他疾病。所有患者均在跑步机上进行运动,工作量逐渐增加,直至达到个人最大工作量。我们监测了心率、呼吸频率、工作量、根据伯格量表得出的主观压力感受以及运动终止的原因。根据吉沃尼给出的公式计算摄氧量。在测试过程中,所有植入的起搏器均程控为VVI 70模式。我们发现,与年龄相关的正常值相比,所有起搏器患者的运动能力均有所下降。特别是房室传导阻滞或缓慢性心律失常患者,其可达到的最大工作量往往甚至未达到诸如上楼等日常活动的水平;病态窦房结综合征患者的运动能力稍好,可能是由于平均心率升高幅度较大。尽管最大工作量存在客观差异,但所有患者在测试结束时的主观感受相同;呼吸频率的变化过程表明,所有人均在个人最大运动能力范围内完成了测试。(摘要截短于250词)

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