Topaloğlu Serdar, Çalık Adnan, Kalaycı Orhan, Sağlam Kutay, Yazıcı Ahmet, Aydın Coşkun
Department of Surgery, Karadeniz Technical University, School of Medicine, Farabi Hospital, Trabzon, Turkey.
Exp Clin Transplant. 2014 Mar;12 Suppl 1:76-80.
Fibrin sealants may prevent hemorrhage and biliary leakage after liver resection. We evaluated the effects of topical fibrin glue application on biliary anastomosis in deceased-donor liver transplant.
From January 2011 to July 2013, fibrin glue was applied around the biliary anastomosis in 10 patients who had deceased-donor liver transplant (recipients: female, 8 patients; median age, 46.9 y) with end-to-end choledochocholedochostomy in 9 patients and hepaticojejunostomy in 1 patient. Biliary leakage was diagnosed with abdominal computed tomography.
Biliary leakage was observed in 1 patient at 18 days after deceased-donor liver transplant with end-to-end choledochocholedochostomy. This was treated with revision laparotomy and reconstruction of the biliary anastomotic leak with a hepaticojejunostomy and placement of an internal stent and fibrin glue; the patient 's condition improved. There were no perioperative deaths.
In deceased-donor liver transplant, application of fibrin glue at the biliary anastomosis may be associated with.
纤维蛋白封闭剂可能预防肝切除术后出血和胆漏。我们评估了局部应用纤维蛋白胶对尸体供肝肝移植中胆管吻合的影响。
2011年1月至2013年7月，10例行尸体供肝肝移植的患者（受者：女性8例；中位年龄46.9岁）在胆管吻合口周围应用纤维蛋白胶，其中9例行端端胆管对端吻合术，1例行肝管空肠吻合术。通过腹部计算机断层扫描诊断胆漏。
1例行端端胆管对端吻合术的尸体供肝肝移植患者在术后18天出现胆漏。通过再次剖腹手术、用肝管空肠吻合术重建胆管吻合口漏口、放置内支架和纤维蛋白胶进行治疗，患者病情改善。无围手术期死亡病例。
在尸体供肝肝移植中，在胆管吻合口应用纤维蛋白胶可能与……有关。
