Yuan Hao, Zhu Xiaofang, Lu Jingting, Dai Jiewen, Fang Bing, Shen Steve G F
Doctor-in-Charge, Department of Oral and Craniomaxillofacial Science, Ninth People's Hospital, College of Stomatology, School of Medicine, Shanghai Jiao Tong University, Shanghai Key Laboratory of Stomatology, Shanghai, China.
Resident, Department of Oral and Craniomaxillofacial Science, Ninth People's Hospital, College of Stomatology, School of Medicine, Shanghai Jiao Tong University, Shanghai Key Laboratory of Stomatology, Shanghai, China.
J Oral Maxillofac Surg. 2014 Apr;72(4):764-72. doi: 10.1016/j.joms.2013.09.007.
In surgery-first accelerated orthognathic surgery, the clinical phenomenon of accelerated orthodontic tooth movement after osteotomy is a benefit compared with the conventional approach. However, because much of the literature on this phenomenon is based on empirical evidence and case reports, experimental animal-based studies are needed to verify and quantify this acceleration effect. The purpose of this prospective experimental study was to identify whether osteotomy procedures increase tooth movement.
Le Fort I osteotomies were performed on the left maxillas in 15 male adult Sprague-Dawley rats. After surgery, a continuous force of 0.5 N was placed on the maxillary left first molar to move the tooth mesially. Another 15 rats had no surgery and served as controls. On days 1, 14, and 28, digital caliper measurements were taken to record tooth movement.
In the experimental group, the maxillary left first molars moved significantly more rapidly on days 14 and 28 (P < .05). Histologic findings showed more active alveolar bone remodeling.
Le Fort I osteotomy significantly accelerated the rate of orthodontic tooth movement. Histologically, more active and extensive bone remodeling was observed after osteotomy.
在手术优先的加速正颌外科手术中，截骨术后正畸牙齿移动加速这一临床现象相较于传统方法是一个优势。然而，由于关于这一现象的许多文献基于经验证据和病例报告，因此需要基于实验动物的研究来验证和量化这种加速效果。这项前瞻性实验研究的目的是确定截骨手术是否会增加牙齿移动。
对15只成年雄性斯普拉格-道利大鼠的左上颌进行Le Fort I型截骨术。术后，对上颌左侧第一磨牙施加0.5 N的持续力使其近中移动。另外15只大鼠未进行手术作为对照。在第1、14和28天，用数字卡尺测量以记录牙齿移动情况。
在实验组中，上颌左侧第一磨牙在第14天和28天移动明显更快（P < .05）。组织学结果显示牙槽骨重塑更活跃。
Le Fort I型截骨术显著加速了正畸牙齿移动的速度。组织学上，截骨术后观察到更活跃和广泛的骨重塑。
