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闪烁扫描术在肝动脉灌注泵化疗中确定最佳灌注的作用

Role of scintigraphy in establishing optimal perfusion in hepatic arterial infusion pump chemotherapy.

作者信息

Savolaine E R, Zeiss J, Schlembach P J, Skeel R T, McCann K, Merrick H W

机构信息

Department of Radiology, Medical College of Ohio, Toledo 43699.

出版信息

Am J Clin Oncol. 1989 Feb;12(1):68-74. doi: 10.1097/00000421-198902000-00016.

DOI:10.1097/00000421-198902000-00016
PMID:2463753
Abstract

Since 1982, physicians at the Medical College of Ohio, Toledo, have performed 41 hepatic intraarterial chemotherapy infusion pump implantations for palliative treatment of metastatic liver disease from various primary tumors of the gastrointestinal tract. Radionuclide hepatic arterial pump imaging has proven to be a very reliable, cost-effective, and uncomplicated method of evaluating liver perfusion as it relates to pump function, catheter integrity, and positioning. Confirmation of satisfactory hepatic perfusion is the key to acceptable treatment by this modality. In combination with periodic computed tomography (CT) scanning and CEA determinations, scintigraphy plays a major role in establishing effective therapy and aids in determining causal factors behind treatment failures.

摘要

自1982年以来,俄亥俄州托莱多市医学院的医生们已进行了41例肝动脉内化疗灌注泵植入手术,用于姑息治疗源自胃肠道各种原发性肿瘤的转移性肝病。放射性核素肝动脉泵成像已被证明是一种非常可靠、经济高效且操作简单的方法,可用于评估与泵功能、导管完整性和定位相关的肝脏灌注情况。确认肝脏灌注良好是采用这种治疗方式取得可接受疗效的关键。与定期计算机断层扫描(CT)和癌胚抗原(CEA)测定相结合,闪烁扫描在确立有效治疗方案以及协助确定治疗失败背后的因果因素方面发挥着重要作用。

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