直肠癌根治术后同期单发肾上腺转移长期生存 1 例

A Case of Long-term Survival after Curative Resection for Synchronous Solitary Adrenal Metastasis from Rectal Cancer.

机构信息

Linlin Chen, MD, Department of Colorectal Surgery, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310016, China.

Da Wang, MD, Department of Colorectal Surgery, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310016, China.

出版信息

Pak J Med Sci. 2014 Jan;30(1):216-9. doi: 10.12669/pjms.301.4341.

DOI:10.12669/pjms.301.4341

PMID:24639864

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3955575/

Abstract

Clinically curable adrenal metastasis is rare. We report a case of synchronous solitary adrenal metastasis from rectal cancer in a 51-year-old man who underwent curative resection. A right adrenal mass was found by ultrasonography during his routine physical examination and this was confirmed by computed tomography (CT). His serum carcinoembryonic antigen (CEA) level was found elevated, and colonoscopy revealed a rectal tumor located 10cm from anal verge. A simultaneous laparoscopic right adrenalectomy and anterior resection for rectal carcinoma was performed. Histopathological examination revealed well-differentiated rectal adenocarcinoma with adrenal metastasis. The patient is still alive and free from disease 6 years after the surgery. A review in the literature showed that synchronous solitary adrenal metastasis from colorectal carcinoma is very rare. Surgical resection and for selected patients, laparoscopic procedure may provide survival benefit and potential surgical cure for a solitary metastasis.

摘要

临床上可治愈的肾上腺转移瘤很少见。我们报告了一例 51 岁男性直肠癌的同步孤立性肾上腺转移病例，该患者接受了根治性切除术。在常规体检中通过超声检查发现右侧肾上腺肿块，计算机断层扫描（CT）证实了这一点。他的血清癌胚抗原（CEA）水平升高，结肠镜检查发现距肛门 10cm 处直肠有一个肿瘤。同时进行了腹腔镜右侧肾上腺切除术和直肠癌前切除术。组织病理学检查显示分化良好的直肠腺癌伴肾上腺转移。手术后 6 年，患者仍存活且无疾病。文献复习显示，结直肠癌的同步孤立性肾上腺转移非常罕见。对于某些患者，手术切除和腹腔镜手术可能为孤立性转移提供生存获益和潜在的手术治愈机会。