Papierska Lucyna, Cwikła Jarosław B, Misiorowski Waldemar, Rabijewski Michał, Sikora Krzysztof, Wanyura Hubert
Clinic of Endocrinology, Medical Center of Postgraduate Education, Warsaw, Poland.
Department of Radiology, The Faculty of Medical Sciences, University of Warmia and Mazury, Olsztyn, Poland.
Case Rep Endocrinol. 2014;2014:492789. doi: 10.1155/2014/492789. Epub 2014 Feb 3.
A 40-year-old patient was referred to Clinic of Endocrinology due to hypophosphatemia causing pain, cramps, and weakness of muscles. Moreover, his bone mineral density was very low. The previous treatment with phosphorus and active vitamin D metabolites was ineffective. In lab tests the hypophosphatemia, hyperphosphaturia, and elevated FGF23 levels were found. Somatostatin receptor scintigraphy (SRS) showed increased radiotracer uptake in the right maxillary sinus and CT scans confirmed presence of tumor in this localization. Biopsy and cytological examination created suspicion of mesenchymal tumor-glomangiopericytoma. Waiting for surgery the patient was treated with long acting Somatostatine analogue, and directly before operation short acting Octreotide and intravenous phosphorus were used. Histology confirmed the cytological diagnosis and the phosphatemia return to normal values in 10 days after the tumor removal.
一名40岁患者因低磷血症导致疼痛、痉挛和肌肉无力，被转诊至内分泌科诊所。此外，他的骨矿物质密度非常低。先前使用磷和活性维生素D代谢物的治疗无效。实验室检查发现有低磷血症、高磷尿症和FGF23水平升高。生长抑素受体闪烁显像（SRS）显示右上颌窦放射性示踪剂摄取增加，CT扫描证实在该部位存在肿瘤。活检和细胞学检查怀疑为间叶性肿瘤——血管球性血管外皮细胞瘤。在等待手术期间，患者接受了长效生长抑素类似物治疗，在手术前直接使用了短效奥曲肽和静脉注射磷。组织学证实了细胞学诊断，肿瘤切除后10天血磷恢复到正常水平。
