松弛素样因子/胰岛素样肽3受体RXFP2在公猪睾丸中的表达与定位
Expression and localization of RLF/ INSL3 receptor RXFP2 in boar testes.
作者信息
Kohsaka Tetsuya, Sagata Dai, Minagawa Itaru, Kohriki Hiroshi, Pitia Ali Mohammed, Sugii Yusuke, Morimoto Masashi, Uera Naoto, Shibata Masatoshi, Sasada Hiroshi, Hasegawa Yoshihisa
出版信息
Ital J Anat Embryol. 2013;118(1 Suppl):23-5.
This study investigated the possibility of the presence of specific receptor for relaxin-like factor (RLF)/insulin-like peptide 3 (INSL3) in boar testes. While RLF/INSL3 was produced by Leydig cells in the boar testis, its own receptor RXFP2 was expressed mainly in meiotic and post-meiotic germ cells, but not in Leydig cells, suggesting the existence of RLF/INSL3-RXFP2 signaling in germ cells of boars.
本研究调查了在公猪睾丸中存在松弛素样因子（RLF）/胰岛素样肽3（INSL3）特异性受体的可能性。虽然RLF/INSL3由公猪睾丸中的睾丸间质细胞产生，但其自身受体RXFP2主要在减数分裂期和减数分裂后生殖细胞中表达，而不在睾丸间质细胞中表达，这表明在公猪生殖细胞中存在RLF/INSL3-RXFP2信号通路。
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