Karasoy Yeşilada Ayşin, Bayraktaroğlu Serdar Bora, Sevim Kamuran Zeynep, Sakız Damlanur, Tatlıdede H Soner
Department of Plastic and Reconstructive Surgery, Şişli Etfal Training and Research Hospital, İstanbul, Turkey.
Freelance Physician, Plastic and Reconstructive Surgery, İstanbul, Turkey.
Acta Orthop Traumatol Turc. 2014;48(1):92-7. doi: 10.3944/AOTT.2014.3212.
The aim of this study was to examine if the application of Ankaferd Blood Stopper (ABS) reduces the number of sutures and therefore reduces anastomosis completion time in a unilateral end-to-end sleeve fish-mouth anastomosis model.
Femoral artery end-to-end unilateral fish-mouth anastomosis models were created from the right and left femoral arteries of 14 male Wistar albino rats (weight: 250 to 300 grams) and divided into 2 equal groups. Rats in Group A received ABS and Group B was the control group. Rats were further divided into equal 2 subgroups, and anastomoses of rats in Group 1A and 1B were explored on the 7th day and on the 14th day in Group 2A and 2B. The groups were compared for anastomosis completion time, macroscopic and microscopic patency, existence of microaneurysm and inflammatory response.
In the ABS group (1A and 2A), mean anastomosis completion time was 13:00±1.50 minutes, and 18:56±2.5 minutes in the control groups (1B and 2B). This difference was statistically significant (p=0.001).
Ankaferd Blood Stopper may be used to reduce the number of sutures and shorten the completion time of artery-to-artery anastomosis of arteries with small diameter and low blood flow rate.
本研究旨在探讨在单侧端端袖状鱼嘴吻合模型中，应用安卡福德止血剂（ABS）是否能减少缝线数量，从而缩短吻合完成时间。
从14只雄性Wistar白化大鼠（体重：250至300克）的左右股动脉建立股动脉端端单侧鱼嘴吻合模型，并分为两组。A组大鼠接受ABS，B组为对照组。大鼠进一步分为两个相等的亚组，1A组和1B组的大鼠在第7天进行吻合，2A组和2B组在第14天进行吻合。比较两组的吻合完成时间、宏观和微观通畅情况、微动脉瘤的存在情况以及炎症反应。
在ABS组（1A和2A），平均吻合完成时间为13:00±1.50分钟，对照组（1B和2B）为18:56±2.5分钟。这种差异具有统计学意义（p = 0.001）。
安卡福德止血剂可用于减少缝线数量，并缩短小直径、低血流速率动脉的动脉对动脉吻合的完成时间。
