Pawlikowska-Warych Małgorzata, Deptuła Wiesław
Department of Microbiology, Faculty of Biology, University of Szczecin, Szczecin, Poland.
Acta Biochim Pol. 2014;61(1):63-5. Epub 2014 Mar 18.
Pathogenic bacteria cause many diseases, some of which are fatal. For researchers, it is a challenge to understand bacterial mechanisms of pathogenicity, including their virulence pathways regulated by RNA. This work presents data on the mechanisms of regulation and expression of several virulence factors coded by RNA, namely 5' UTR fragments, riboswitches and small non-coding RNA (sRNA).
致病细菌会引发多种疾病，其中一些是致命的。对于研究人员而言，了解细菌的致病机制，包括其由RNA调控的毒力途径，是一项挑战。这项工作展示了关于几种由RNA编码的毒力因子的调控和表达机制的数据，即5'非翻译区片段、核糖开关和小非编码RNA（sRNA）。
