Baden H P, Byers H R, Goldaber M
Harvard Medical School, Department of Dermatology, Massachusetts General Hospital, Boston 02114.
Cutis. 1989 Jan;43(1):41-3.
Psoriasis occurring in a patient with lamellar ichthyosis is reported. Similar self-limited episodes had occurred earlier. On histopathologic examination of a biopsy specimen, an eruptive plaque showed parakeratosis and a reduction in the granular layer. Electrophoretic analysis of the keratins isolated from the epidermis of a plaque showed a reduction in the amount of the 67 kd polypeptide compared to the keratins of ichthyosis epidermis. Both of these findings support the diagnosis of psoriasis. Epilyt, applied daily, was effective in removing scales.
报告了1例发生在板层状鱼鳞病患者身上的银屑病。类似的自限性发作早些时候也曾出现过。对活检标本进行组织病理学检查，一个发疹性斑块显示角化不全和颗粒层减少。对从斑块表皮分离出的角蛋白进行电泳分析，结果显示与鱼鳞病表皮的角蛋白相比，67 kd多肽的量减少。这两项发现均支持银屑病的诊断。每天外用Epilyt可有效去除鳞屑。
