Nagata K, Tagawa K, Hiroi S, Shishido F, Uemura K
Department of Neurology, Research Institute for Brain and Blood Vessels, Akita, Japan.
Electroencephalogr Clin Neurophysiol. 1989 Jan;72(1):16-30. doi: 10.1016/0013-4694(89)90027-8.
Quantitative EEG data were analyzed statistically with respect to cortical cerebral blood flow (CBF) and oxygen metabolism (CMRO2) measured by positron emission tomography in 47 patients with unilateral cerebral infarction. Relative value of the square root of average power was used as a percentage power fraction (PPF) for each frequency category. Power ratio index (PRI) was calculated by dividing the combined delta-PPF and theta-PPF by the combined alpha-PPF and beta-PPF. Delta-PPF, theta-PPF and PRI correlated negatively with regional CBF (rCBF) and CMRO2 (rCMRO2) whereas alpha-PPF and beta-PPF correlated positively. In the acute stage, delta-PPF, alpha-PPF and PRI correlated with rCBF at all but the frontopolar region whereas the correlation with rCMRO2 was poor. Alpha-PPF and PRI correlated also with rCMRO2 in the frontal, central, parietal and occipital regions while delta-PPF correlated with rCBF only in the parietal and occipital regions in the subacute stage. In the chronic stage, all EEG quotients correlated significantly with both rCBF and CMRO2 in the central and parietal regions. In the frontopolar region, only the theta-PPF correlated with rCBF throughout. In the comparison of hemispheric mean values, the correlations were always closer for the affected hemisphere than for the contralateral hemisphere. Although hemispheric mean CBF and CMRO2 were significantly lower in patients with cortical infarcts on CT than in those with small subcortical infarcts, there was no significant difference in the EEG data between the 2 groups.
对47例单侧脑梗死患者的定量脑电图数据进行了统计学分析，这些数据与通过正电子发射断层扫描测量的皮质脑血流量（CBF）和氧代谢（CMRO2）相关。平均功率平方根的相对值用作每个频率类别的功率分数百分比（PPF）。功率比指数（PRI）通过将δ-PPF和θ-PPF之和除以α-PPF和β-PPF之和来计算。δ-PPF、θ-PPF和PRI与局部脑血流量（rCBF）和CMRO2（rCMRO2）呈负相关，而α-PPF和β-PPF呈正相关。在急性期，除额极区外，δ-PPF、α-PPF和PRI与rCBF相关，而与rCMRO2的相关性较差。在亚急性期，α-PPF和PRI在额叶、中央、顶叶和枕叶区域也与rCMRO2相关，而δ-PPF仅在顶叶和枕叶区域与rCBF相关。在慢性期，所有脑电图商数在中央和顶叶区域与rCBF和CMRO2均显著相关。在额极区，只有θ-PPF始终与rCBF相关。在半球平均值的比较中，患侧半球的相关性总是比健侧半球更密切。尽管CT显示皮质梗死患者的半球平均CBF和CMRO2显著低于小皮质下梗死患者，但两组的脑电图数据无显著差异。
