Cheon Yun-Hong, Kim Min-Gyo, Kim Ji-Eun, Ha Chang Yoon, Lee Sang-Il, Kim Hyun-Ok
a Department of Internal medicine and Institute of Health Science , Gyeongsang National University School of Medicine , Jinju , South Korea.
b Department of Radiology , Gyeongsang National University School of Medicine , Jinju , South Korea.
Mod Rheumatol. 2016;26(3):450-3. doi: 10.3109/14397595.2014.891494. Epub 2014 Mar 19.
Here, we report the case of a 69-year-old man with limited granulomatosis with polyangiitis (GPA; formerly Wegener's granulomatosis) who developed papillary thyroid cancer, adenocarcinoma of the stomach, and myelodysplastic syndrome following glucocorticoid treatment. This is the first report to present multiple malignancies in a patient with limited GPA without immunosuppressive treatment. Thus, our report supports the notion that limited GPA itself can be associated with the development of malignancy.
在此,我们报告一例69岁患有局限性肉芽肿性多血管炎(GPA;既往称韦格纳肉芽肿)的男性患者,其在接受糖皮质激素治疗后发生了甲状腺乳头状癌、胃腺癌和骨髓增生异常综合征。这是首例关于未接受免疫抑制治疗的局限性GPA患者发生多种恶性肿瘤的报告。因此,我们的报告支持局限性GPA本身可能与恶性肿瘤发生相关这一观点。