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一名患有局限性肉芽肿性多血管炎且未接受免疫抑制治疗的患者出现多种恶性肿瘤。

Multiple malignancies in a patient with limited granulomatosis with polyangiitis without immunosuppressive therapy.

作者信息

Cheon Yun-Hong, Kim Min-Gyo, Kim Ji-Eun, Ha Chang Yoon, Lee Sang-Il, Kim Hyun-Ok

机构信息

a Department of Internal medicine and Institute of Health Science , Gyeongsang National University School of Medicine , Jinju , South Korea.

b Department of Radiology , Gyeongsang National University School of Medicine , Jinju , South Korea.

出版信息

Mod Rheumatol. 2016;26(3):450-3. doi: 10.3109/14397595.2014.891494. Epub 2014 Mar 19.

Abstract

Here, we report the case of a 69-year-old man with limited granulomatosis with polyangiitis (GPA; formerly Wegener's granulomatosis) who developed papillary thyroid cancer, adenocarcinoma of the stomach, and myelodysplastic syndrome following glucocorticoid treatment. This is the first report to present multiple malignancies in a patient with limited GPA without immunosuppressive treatment. Thus, our report supports the notion that limited GPA itself can be associated with the development of malignancy.

摘要

在此,我们报告一例69岁患有局限性肉芽肿性多血管炎(GPA;既往称韦格纳肉芽肿)的男性患者,其在接受糖皮质激素治疗后发生了甲状腺乳头状癌、胃腺癌和骨髓增生异常综合征。这是首例关于未接受免疫抑制治疗的局限性GPA患者发生多种恶性肿瘤的报告。因此,我们的报告支持局限性GPA本身可能与恶性肿瘤发生相关这一观点。

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