Ogawa M, Azemoto R, Makino Y, Mori Y, Ueda S, Wakashin M, Ohto M
First Department of Internal Medicine, Chiba University School of Medicine, Japan.
J Intern Med. 1991 Feb;229(2):189-92. doi: 10.1111/j.1365-2796.1991.tb00329.x.
We present the case of a 16-year-old woman with Wegener's granulomatosis, who developed a pneumothorax while receiving treatment with cyclophosphamide and glucocorticoids. The lung was re-expanded by tube drainage, and the patient recovered completely while the immunosuppressive treatment was continued in combination with sulphamethoxazole-trimethoprim. A possible role for this antimicrobial drug in the treatment of Wegener's granulomatosis is briefly discussed.
