Raubenheimer Erich J, Noffke Claudia E E, Hendrik Hilde D
Oral Pathology and Consultant for Metabolic Bone Diseases, School of Oral Health Sciences, University of Limpopo, Pretoria, South Africa.
J Oral Pathol Med. 2015 Apr;44(4):239-43. doi: 10.1111/jop.12176. Epub 2014 Mar 20.
Chronic kidney disease-mineral bone disorder (CKD-MBD) is a syndrome encompassing skeletal and extra skeletal changes associated with chronic kidney disease. It progresses silently until an advanced clinical stage when complications impact on the quality of life and survival rates of patients. The maxillofacial manifestations are unique and may play an important role in the early identification of changes which could influence the management of these patients. The goal of this review is to highlight the maxillofacial features, pathology, and principles of management of CKD-MBD.
慢性肾脏病-矿物质和骨异常（CKD-MBD）是一种综合征，包括与慢性肾脏病相关的骨骼和骨骼外变化。它在不知不觉中进展，直到进入临床晚期，此时并发症会影响患者的生活质量和生存率。颌面表现独具特色，可能在早期识别那些会影响这些患者治疗的变化方面发挥重要作用。本综述的目的是强调CKD-MBD的颌面特征、病理学及治疗原则。
