Nasrallah June B, Nasrallah Mikhail E
*Department of Plant Biology, Cornell University, 412 Mann Library Building, Ithaca, NY 14853, U.S.A.
Biochem Soc Trans. 2014 Apr;42(2):313-9. doi: 10.1042/BST20130222.
SRK (S-locus receptor kinase) is the receptor that allows stigma epidermal cells to discriminate between genetically related ('self') and genetically unrelated ('non-self') pollen in the self-incompatibility response of the Brassicaceae. SRK and its ligand, the pollen coat-localized SCR (S-locus cysteine-rich protein), are highly polymorphic, and their allele-specific interaction explains specificity in the self-incompatibility response. The present article reviews current knowledge of the role of SRK in the recognition and response phases of self-incompatibility, and highlights the new insights provided by analysis of a transgenic self-incompatible Arabidopsis thaliana model.
SRK（S位点受体激酶）是一种受体，在十字花科植物的自交不亲和反应中，它使柱头表皮细胞能够区分遗传相关的（“自身”）和遗传不相关的（“非自身”）花粉。SRK及其配体——定位于花粉壁的SCR（S位点富含半胱氨酸蛋白）具有高度多态性，它们的等位基因特异性相互作用解释了自交不亲和反应中的特异性。本文综述了目前关于SRK在自交不亲和识别和反应阶段作用的知识，并强调了通过对转基因自交不亲和拟南芥模型分析所提供的新见解。
