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一种用于复杂主动脉手术的安全且灵活的体外循环技术,无需深低温停循环。

A safe and flexible cardiopulmonary bypass technique for complex aortic surgery without the requirement for deep hypothermic circulatory arrest.

作者信息

Machin David, Tams Gemma, Bingham Helen, Abid Qamar, Adem Ahmed

出版信息

J Extra Corpor Technol. 2013 Dec;45(4):254-8.

PMID:24649575
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4557500/
Abstract

This article describes an adaptable technique of full-body perfusion during complex aortic surgery, which was performed on six consecutive patients, at a nasopharyngeal temperature of 28-34 degrees C for a mean duration of 5 hours. A modified perfusion system was used to provide upper and lower body perfusion through axillary and femoral artery cannulation. The option of selective antegrade cerebral perfusion was also available if required. A simple custom-made circuit and application of additional monitoring such as cerebral oximetry makes this technique a safe and flexible method of providing continuous whole-body perfusion at moderate hypothermia and above. We found that these patients all had no major coagulopathies after the procedure and demonstrated no observable neurological, renal, or gastrointestinal dysfunction on recovery.

摘要

本文描述了一种在复杂主动脉手术期间进行全身灌注的适应性技术,该技术连续应用于6例患者,鼻咽温度为28 - 34摄氏度,平均持续时间为5小时。采用改良的灌注系统,通过腋动脉和股动脉插管实现上半身和下半身灌注。如有需要,还可选择选择性顺行性脑灌注。一个简单的定制回路以及应用额外的监测手段如脑血氧饱和度监测,使该技术成为在中度低温及以上提供持续全身灌注的安全且灵活的方法。我们发现这些患者术后均无严重凝血障碍,恢复过程中未出现明显的神经、肾脏或胃肠道功能障碍。

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A safe and flexible cardiopulmonary bypass technique for complex aortic surgery without the requirement for deep hypothermic circulatory arrest.一种用于复杂主动脉手术的安全且灵活的体外循环技术,无需深低温停循环。
J Extra Corpor Technol. 2013 Dec;45(4):254-8.
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本文引用的文献

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The effects of zero-balance ultrafiltration on postoperative recovery after cardiopulmonary bypass: a meta-analysis of randomized controlled trials.零平衡超滤对体外循环术后恢复的影响:一项随机对照试验的荟萃分析
Perfusion. 2012 Sep;27(5):386-92. doi: 10.1177/0267659112450182. Epub 2012 Jun 7.
2
Aortic arch replacement with moderate hyperthomia and a modified 3-pump circuit.采用中度血液稀释和改良三泵体外循环进行主动脉弓置换术。
Perfusion. 2011 Mar;26(2):141-4. doi: 10.1177/0267659110392441. Epub 2010 Dec 20.
3
Evolving arch surgery using integrated antegrade selective cerebral perfusion: impact of axillary artery perfusion.采用整合顺行性选择性脑灌注的不断发展的主动脉弓手术:腋动脉灌注的影响
J Thorac Cardiovasc Surg. 2008 Sep;136(3):641-8; discussion 948-9. doi: 10.1016/j.jtcvs.2008.02.089.
4
Microemboli detection on extracorporeal bypass circuits.体外循环回路中的微栓子检测
Perfusion. 2008 Jan;23(1):23-32. doi: 10.1177/0267659108094350.
5
Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery.心脏手术患者接受红细胞输血后死亡率增加、术后发病率增加及成本增加。
Circulation. 2007 Nov 27;116(22):2544-52. doi: 10.1161/CIRCULATIONAHA.107.698977. Epub 2007 Nov 12.
6
Incomplete circle of Willis and right axillary artery perfusion.大脑 Willis 环不完整及右腋动脉灌注。
Ann Thorac Surg. 2006 Jul;82(1):74-9. doi: 10.1016/j.athoracsur.2006.02.034.
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Oxygen delivery during cardiopulmonary bypass and acute renal failure after coronary operations.体外循环期间的氧输送与冠状动脉手术后的急性肾衰竭
Ann Thorac Surg. 2005 Dec;80(6):2213-20. doi: 10.1016/j.athoracsur.2005.05.069.
8
Antegrade cerebral perfusion with hypothermic circulatory arrest: a case report.低温循环停止下的顺行性脑灌注:一例报告。
Perfusion. 2003 Sep;18(5):303-6. doi: 10.1191/0267659103pf669oa.
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Brain protection using antegrade selective cerebral perfusion: a multicenter study.顺行性选择性脑灌注的脑保护作用:一项多中心研究。
Ann Thorac Surg. 2003 Oct;76(4):1181-8; discussion 1188-9. doi: 10.1016/s0003-4975(03)00824-5.
10
Usefulness of antegrade selective cerebral perfusion during aortic arch operations.
Ann Thorac Surg. 2002 Nov;74(5):S1806-9; discussion S1825-32. doi: 10.1016/s0003-4975(02)04150-4.