Tolwani Ashita J
Division of Nephrology, University of Alabama, Birmingham, Alabama
Clin J Am Soc Nephrol. 2014 Aug 7;9(8):1470-8. doi: 10.2215/CJN.10461013. Epub 2014 Mar 20.
Up to 30% of patients undergoing cardiac surgery develop AKI, with 1% requiring RRT. AKI is an independent risk factor for morbidity and mortality. Postoperatively, even minimal changes in serum creatinine are associated with a substantial increase in mortality. No intervention has been definitely proven effective in reducing kidney injury. The successful prevention and management of AKI involves identifying patients at risk for AKI, recognizing subtle abnormalities in a timely manner, performing basic clinical assessments, and responding appropriately to data obtained. With that in mind, in this Attending Rounds, a woman with AKI in the setting of cardiac surgery is presented to highlight the use of history, physical exam, hemodynamic monitoring, laboratory data trends, and urine indices in establishing the correct diagnosis and appropriate management.
接受心脏手术的患者中,高达30%会发生急性肾损伤(AKI),其中1%需要进行肾脏替代治疗(RRT)。AKI是发病和死亡的独立危险因素。术后,即使血清肌酐的微小变化也与死亡率的大幅上升相关。尚无干预措施被明确证明能有效减少肾损伤。成功预防和管理AKI涉及识别有AKI风险的患者、及时发现细微异常、进行基本临床评估以及对所获数据做出适当反应。考虑到这一点,在本次主治医生查房中,展示了一名在心脏手术背景下发生AKI的女性患者,以突出病史、体格检查、血流动力学监测、实验室数据趋势和尿液指标在确立正确诊断和适当管理中的应用。