Birch Elizabeth, Jenkins Debbie, Noble Simon
Department of Palliative Medicine, Royal Gwent Hospital, Newport, UK.
BMJ Support Palliat Care. 2011 Sep;1(2):189-92. doi: 10.1136/bmjspcare-2011-000052. Epub 2011 Aug 9.
Hypertrophic osteoarthropathy (HOA) is a syndrome most commonly associated with non-small cell lung cancer and consists of periostitis, digital clubbing and painful polyarthropathy. Its symptoms may be disabling and are reportedly difficult to manage effectively with conventional analgesia. We present a case of a lung cancer patient with opioid resistant painful HOA in whom analgesia was achieved with octreotide.
肥厚性骨关节病(HOA)是一种最常与非小细胞肺癌相关的综合征,由骨膜炎、杵状指和疼痛性多关节病组成。其症状可能会使人丧失活动能力,据报道,传统镇痛方法难以有效控制这些症状。我们报告一例肺癌患者,其患有对阿片类药物耐药的疼痛性HOA,使用奥曲肽实现了镇痛。