MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital Cambridge, MA, USA ; Department of Neurology, Harvard Medical School Boston, MA, USA.
Harvard NeuroDiscovery Center, Harvard Medical School Boston, MA, USA.
Front Neuroinform. 2014 Mar 11;8:21. doi: 10.3389/fninf.2014.00021. eCollection 2014.
Social media has the potential to accelerate the pace of biomedical research through online collaboration, discussions, and faster sharing of information. Focused web-based scientific social collaboratories such as the Alzheimer Research Forum have been successful in engaging scientists in open discussions of the latest research and identifying gaps in knowledge. However, until recently, tools to rapidly create such communities and provide high-bandwidth information exchange between collaboratories in related fields did not exist.
We have addressed this need by constructing a reusable framework to build online biomedical communities, based on Drupal, an open-source content management system. The framework incorporates elements of Semantic Web technology combined with social media. Here we present, as an exemplar of a web community built on our framework, the Pain Research Forum (PRF) (http://painresearchforum.org). PRF is a community of chronic pain researchers, established with the goal of fostering collaboration and communication among pain researchers.
Launched in 2011, PRF has over 1300 registered members with permission to submit content. It currently hosts over 150 topical news articles on research; more than 30 active or archived forum discussions and journal club features; a webinar series; an editor-curated weekly updated listing of relevant papers; and several other resources for the pain research community. All content is licensed for reuse under a Creative Commons license; the software is freely available. The framework was reused to develop other sites, notably the Multiple Sclerosis Discovery Forum (http://msdiscovery.org) and StemBook (http://stembook.org).
Web-based collaboratories are a crucial integrative tool supporting rapid information transmission and translation in several important research areas. In this article, we discuss the success factors, lessons learned, and ongoing challenges in using PRF as a driving force to develop tools for online collaboration in neuroscience. We also indicate ways these tools can be applied to other areas and uses.
社交媒体通过在线协作、讨论和更快地共享信息，有潜力加速生物医学研究的步伐。专注于网络的科学社交协作平台，如阿尔茨海默病研究论坛，已经成功地让科学家们参与到最新研究的公开讨论中，并发现了知识的空白。然而，直到最近，还没有快速创建此类社区的工具，也无法在相关领域的协作平台之间提供高带宽的信息交换。
我们通过构建一个基于 Drupal 的可重复使用框架来满足这一需求，Drupal 是一个开源的内容管理系统。该框架结合了语义 Web 技术和社交媒体的元素。在这里，我们以我们的框架构建的在线生物医学社区的一个示例，即疼痛研究论坛（PRF）（http://painresearchforum.org）为例。PRF 是一个慢性疼痛研究人员社区，旨在促进疼痛研究人员之间的合作和交流。
PRF 于 2011 年推出，拥有超过 1300 名注册会员，并允许他们提交内容。它目前拥有超过 150 篇关于研究的专题新闻文章；30 多个活跃或存档的论坛讨论和期刊俱乐部功能；一个网络研讨会系列；一个由编辑策划的每周更新的相关论文清单；以及其他几个疼痛研究社区的资源。所有内容均根据知识共享许可协议获得再许可；该软件是免费提供的。该框架被重新用于开发其他网站，特别是多发性硬化症发现论坛（http://msdiscovery.org）和 StemBook（http://stembook.org）。
基于网络的协作平台是支持几个重要研究领域快速信息传输和转化的关键集成工具。在本文中，我们讨论了使用 PRF 作为推动神经科学在线协作工具开发的动力的成功因素、经验教训和持续挑战。我们还指出了这些工具可以应用于其他领域和用途的方式。
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