Nee R, Fitzgerald M
Ir Med J. 2014 Feb;107(2):48, 50.
We wish to report two cases of methaemoglobinaemia secondary to amyl nitrate use. A 55-year-old male presented with saturations in the mid 80s despite FiO2 of 1.0 and GCS 10 and a 22-year-old female who presented with fluctuating GCS and a slate grey colour. Both were found to have high levels of metheamoglobinaemia on ABG, were treated with methylene blue and made excellent recoveries. These cases illustrate the risk of methaemoglobinaemia secondary to amyl nitrate. Appropriate and prompt management can lead to very good outcomes.
我们希望报告两例因使用亚硝酸异戊酯继发高铁血红蛋白血症的病例。一名55岁男性,尽管吸入氧浓度为1.0且格拉斯哥昏迷评分(GCS)为10,但血氧饱和度仍处于80%左右;另一名22岁女性,表现为GCS波动及皮肤呈青灰色。两人动脉血气分析均显示高铁血红蛋白血症水平升高,经亚甲蓝治疗后恢复良好。这些病例说明了因亚硝酸异戊酯继发高铁血红蛋白血症的风险。恰当及时的处理可带来非常好的治疗效果。