Okonsky Jennifer G, Webel Allison, Rose Carol Dawson, Johnson Mallory, Asher Alice, Cuca Yvette, Kaihura Alphoncina, Hanson Jan E, Portillo Carmen J
a Department of Community Health Systems, School of Nursing , University of California San Francisco , San Francisco , California , USA.
Health Care Women Int. 2015 Sep;36(9):1007-25. doi: 10.1080/07399332.2014.903952. Epub 2014 May 15.
Women aged 15-24 years have an HIV infection rate twice that of men the same age. In this study we examined reasons why HIV-infected women taking antiretroviral therapy (ART) report missing HIV medications. Women (N = 206) on ART were 2.2 times more likely to endorse reasons pertaining to forgetfulness versus reasons pertaining to problems taking pills (OR = 2.2, 95% CI = 1.63, 2.94, p <.001). There was a difference between the adherent and nonadherent groups in types of reasons overall (p <.001, 95% CI = -3.82, -2.03). Using a patient-centered approach to understand type of nonadherence (intentional vs. unintentional) may support development of novel interventions.
15至24岁女性的艾滋病毒感染率是同龄男性的两倍。在本研究中,我们调查了接受抗逆转录病毒疗法(ART)的感染艾滋病毒的女性报告漏服艾滋病毒药物的原因。接受ART治疗的女性(N = 206)认可与健忘有关的原因的可能性是认可与吞服药物问题有关的原因的2.2倍(OR = 2.2,95% CI = 1.63,2.94,p <.001)。总体而言,依从组和不依从组在原因类型上存在差异(p <.001,95% CI = -3.82,-2.03)。采用以患者为中心的方法来理解不依从的类型(故意与非故意)可能有助于开发新的干预措施。