An Tianzhi, Moon Eunice, Bullen Jennifer, Kapoor Baljendra, Wu Alex, Sands Mark, Wang Weiping
Imaging Institute, Section of Interventional Radiology, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195.
Department of Quantitative Health Sciences, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195.
J Vasc Interv Radiol. 2014 Jun;25(6):941-8. doi: 10.1016/j.jvir.2014.01.035. Epub 2014 Mar 18.
To investigate the prevalence and clinical sequelae of G2 filter (Bard Peripheral Vascular, Tempe, Arizona) fractures and fragment migration.
Patients who underwent G2 filter placement between October 2005 and February 2010 were assessed for filter fractures and complications. Fracture prevalence was estimated at various time points based on data from patients with known fracture status.
Among 829 patients who underwent G2 filter placement, 684 had follow-up imaging and qualified for the study (381 men and 303 women; average age, 60.3 y; range, 15.8-95.2 y). For 541 (79%) patients, at least one image was available that contained the filter (imaging follow-up interval, 14.9 mo ± 20.0; range, 0-78.6 mo); images that did not include the filter but may have shown the migrated fracture fragment were available for 143 (21%) patients (follow-up interval, 11.2 mo ± 19.3; range, 0-83.4 mo). There were 16 fractured limbs identified in 13 patients (incidence, 1.9%; follow-up interval, 30.4 mo ± 18.7; range, 5.5-76.5 mo). Fracture fragments were identified in the pulmonary arteries (n = 4), right ventricle (n = 2), pericardium (n = 1), iliac vein (n = 1), and kidney (n = 1). Four fracture limbs remained near the filter; the remaining three could not be located. All patients with filter fracture were asymptomatic. The estimated 5-year fracture prevalence was 38% (95% confidence interval, 22.9%, 54.8%).
The early occurrence of G2 filter fractures was low, but the incidence increased over time. No life-threatening events occurred in patients with filter fracture during the study time frame.
研究G2滤器（巴德外周血管公司，亚利桑那州坦佩）骨折及碎片移位的发生率和临床后果。
对2005年10月至2010年2月期间接受G2滤器置入的患者进行滤器骨折及并发症评估。根据已知骨折状态患者的数据，估计不同时间点的骨折发生率。
在829例接受G2滤器置入的患者中，684例有随访影像且符合研究条件（男性381例，女性303例；平均年龄60.3岁；范围15.8 - 95.2岁）。541例（79%）患者至少有一张包含滤器的影像（影像随访间隔为14.9个月±20.0；范围0 - 78.6个月）；143例（21%）患者有不包含滤器但可能显示移位骨折碎片的影像（随访间隔为11.2个月±19.3；范围0 - 83.4个月）。13例患者中有16条肢体发生骨折（发生率1.9%；随访间隔为30.4个月±18.7；范围5.5 - 76.5个月）。在肺动脉（n = 4）、右心室（n = 2）、心包（n = 1）、髂静脉（n = 1）和肾脏（n = 1）中发现骨折碎片。4条骨折肢体仍靠近滤器；其余3条无法定位。所有滤器骨折患者均无症状。估计5年骨折发生率为38%（95%置信区间，22.9%，54.8%）。
G2滤器骨折早期发生率较低，但随时间推移发生率增加。在研究时间段内，滤器骨折患者未发生危及生命的事件。
