δ 阿片受体的轻触。

The light touch of delta opioid receptors.

机构信息

Discipline of Pharmacology, The University of Sydney, Sydney, NSW 2006, Australia.

出版信息

Neuron. 2014 Mar 19;81(6):1220-1222. doi: 10.1016/j.neuron.2014.03.004.

DOI:10.1016/j.neuron.2014.03.004

Abstract

Expression of δ-opioid receptors in sensory neurons is controversial. In this issue of Neuron, Bardoni et al. (2014) present evidence that DOPrs are expressed on mechanosensory neurons involved in detecting nonnoxious touch but are very sparse in μ-opioid receptor-rich nociceptive neurons.

摘要

δ-阿片受体在感觉神经元中的表达存在争议。在本期《神经元》杂志上，Bardoni 等人（2014）提出证据表明，DOPrs 表达于参与探测非伤害性触觉的机械感觉神经元上，但在富含 μ-阿片受体的伤害性神经元中则非常稀疏。