Division of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong.
Division of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong.
J Biomech. 2014 May 7;47(7):1658-64. doi: 10.1016/j.jbiomech.2014.02.036. Epub 2014 Mar 5.
Deep tissue injury (DTI) occurs in deep muscles around bony prominences due to excessive and prolonged mechanical loading acting on the skin surface. The condition is clinically challenging because it can escape being noticed till the damage propagates all the way to the skin. In this study, a semi-3D finite element model of a human buttock was used to simulate the process of ulcer evolution based on our recent damage accumulation and repair theory for DTI. The theory included not only the loading damage, but also further reperfusion and inflammatory injuries upon unloading. The results showed that depending on the model parameters and loading conditions, a deep tissue ulcer may initiate around a bony prominence and expand to affect the entire tissue thickness. The damage evolution can be affected by the tissue healing rate, the loading-unloading pattern and the cushion stiffness. The results may help clinical workers appreciate the importance of proper patient turning and the appropriate choice of cushion.
深部组织损伤（DTI）发生在骨隆突周围的深部肌肉，是由于作用于皮肤表面的过度和长时间的机械负荷。这种情况具有临床挑战性，因为它可能会被忽视，直到损伤一直传播到皮肤。在这项研究中，使用人体臀部的半 3D 有限元模型，根据我们最近的 DTI 损伤积累和修复理论，模拟溃疡演变过程。该理论不仅包括加载损伤，还包括卸载时进一步的再灌注和炎症损伤。结果表明，根据模型参数和加载条件，深部组织溃疡可能在骨隆突周围开始，并扩展到影响整个组织厚度。损伤演变可能受到组织愈合率、加载-卸载模式和坐垫硬度的影响。研究结果可能有助于临床工作者认识到正确翻身和适当选择坐垫的重要性。
