d'Agostino Cristina, Romeo Pietro, Lavanga Vito, Pisani Salvatore, Sansone Valerio
Rheumatol Int. 2014 Nov;34(11):1513-8. doi: 10.1007/s00296-014-2991-5.
There is no gold standard for treatment of bone marrow edema syndrome of the hip (BMESH). Usually, treatment is conservative, owing to the favorable and self limiting prognosis. In musculoskeletal disorders, the effectiveness of extracorporeal shock wave therapy (ESWT) has been widely recognized and recent research supports its use in the treatment of the first stages of avascular osteonecrosis of the proximal femur and in other conditions where bone marrow edema is present. On this basis, we performed a prospective study to evaluate the effectiveness of ESWT in normalizing the symptoms and imaging features of BMESH. Twenty consecutive symptomatic patients underwent two treatments of high-energy ESWT and were followed-up at 2, 3 and 6 months, with a final clinical follow-up at mean 15.52 ± 1.91 months. Patients underwent magnetic resonance imaging of the hip and were evaluated according to the Harris hip score. The mean improvement in HHS over the course of the study was of 58.5 ± 14.9 points (p < 0.0001), and the mean edema area reduced from 981.9 ± 453.2 mm(2) pre-treatment to 107.8 ± 248.1 mm(2) at 6 months. ESWT seems to be a powerful, non-pharmacological tool that produces rapid pain relief and functional improvement and aids the normalization of the vascular and metabolic impairments which characterize BMESH.
对于髋关节骨髓水肿综合征(BMESH),目前尚无金标准治疗方法。通常,由于其预后良好且具有自限性,治疗以保守为主。在肌肉骨骼疾病中,体外冲击波疗法(ESWT)的有效性已得到广泛认可,最近的研究支持将其用于治疗股骨近端缺血性坏死的第一阶段以及其他存在骨髓水肿的病症。在此基础上,我们进行了一项前瞻性研究,以评估ESWT在使BMESH的症状和影像学特征恢复正常方面的有效性。连续20例有症状的患者接受了两次高能ESWT治疗,并在2、3和6个月时进行随访,最终临床随访平均时间为15.52±1.91个月。患者接受了髋关节磁共振成像检查,并根据Harris髋关节评分进行评估。在研究过程中,HHS的平均改善为58.5±14.9分(p<0.0001),平均水肿面积从治疗前的981.9±453.2mm²减少到6个月时的107.8±248.1mm²。ESWT似乎是一种有效的非药物工具,能迅速缓解疼痛、改善功能,并有助于使BMESH所特有的血管和代谢损伤恢复正常。