Thederan L, Grehn F, Klink T
Dept. of Ophthalmology, Universitäts-Augenklinik, Würzburg.
Klin Monbl Augenheilkd. 2014 Mar;231(3):256-61. doi: 10.1055/s-0033-1360392. Epub 2014 Mar 21.
Trabeculectomy (TET) is still the gold standard in incisional glaucoma surgery. It achieves an efficient intraocular pressure (IOP) reduction. Unfortunately postsurgical complications of the procedure are frequent. Canaloplasty is a non-penetrating procedure, which aims at restoration of the natural aqueous outflow pathways, without subconjunctival drainage.
This study has compared both surgical procedures concerning IOP, defined success criteria, postoperative medication, visual acuity and postoperative complications/interventions.
In a retrospective study 22 eyes after trabeculectomy and 22 eyes after canaloplasty were included. IOP, complete and qualified success, postoperative medication, visual acuity and complications/interventions were recorded at 6 month, 12 month and at last follow-up postoperatively.
The mean IOP in the trabeculectomy and canaloplasty groups decreased from 23.91 ± 10.68 mmHg to 10.82 ± 3.67 mmHg and from 23.68 ± 7.57 mmHg to 14.50 ± 3.80 mmHg, respectively. The postoperative complications and interventions between the two groups did not reveal a statistically significant difference. Complete success (IOP < 21 mmHg and 20 % IOP reduction from baseline without medication) was achieved in 18 eyes (81.8 %) after trabeculectomy and in 11 eyes (50.0 %) after canaloplasty (p = 0.026).
Canaloplasty and trabeculectomy are safe and effective procedures in the treatment of open-angle glaucoma. Both surgical methods reduce the IOP and the postoperative medication to a statistically significant extent. Trabeculectomy attains higher long-term complete success rates accompanied by slightly increased early postoperative complication rates (n. s.), compared to canaloplasty.
小梁切除术(TET)仍是切开性青光眼手术的金标准。它能有效降低眼压(IOP)。不幸的是,该手术的术后并发症很常见。睫状体光凝术是一种非穿透性手术,旨在恢复自然房水流出途径,无需结膜下引流。
本研究比较了两种手术在眼压、定义的成功标准、术后用药、视力以及术后并发症/干预方面的情况。
在一项回顾性研究中,纳入了22例行小梁切除术后的眼睛和22例行睫状体光凝术后的眼睛。记录术后6个月、12个月以及最后一次随访时的眼压、完全成功和合格成功情况、术后用药、视力以及并发症/干预情况。
小梁切除术组和睫状体光凝术组的平均眼压分别从23.91±10.68 mmHg降至10.82±3.67 mmHg以及从23.68±7.57 mmHg降至14.50±3.80 mmHg。两组之间的术后并发症和干预情况未显示出统计学上的显著差异。小梁切除术后18只眼(81.8%)实现了完全成功(眼压<21 mmHg且眼压较基线降低20%且无需用药),睫状体光凝术后11只眼(50.0%)实现了完全成功(p = 0.026)。
睫状体光凝术和小梁切除术在开角型青光眼治疗中是安全有效的手术。两种手术方法均能在统计学上显著降低眼压和术后用药量。与睫状体光凝术相比,小梁切除术获得更高的长期完全成功率,同时术后早期并发症发生率略有增加(无统计学意义)。